Shoulder–pelvis PNF exercises versus suboccipital release for chronic neck pain with tight hamstrings
Official title: Symmetrical Scapula-pelvis Proprioceptive Neuromuscular Facilitation and Superficial Back Line in Chronic Neck Pain With Hamstring Tightness
Run by University of Karachi · NCT07332845 · Data updated 2026-11-12
This project will test whether a shoulder-to-pelvis PNF exercise program helps 18–40-year-olds with chronic neck pain and tight hamstrings more than suboccipital muscle release combined with hamstring stretching.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 156 (estimated) |
| Sponsor | University of Karachi Academic / other |
| Locations | 1 site (Karachi, Sindh) |
| Status | Recruiting |
| Started | January 16, 2026 |
| Main results expected | October 26, 2026 |
| Study ends | November 26, 2026 |
| Registry record updated | March 10, 2026 |
| Trial ID | NCT07332845 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–40 with chronic neck pain (>3 months) and measurable hamstring tightness who have not had spinal surgery and have no progressive neurological deficits are ideal candidates.
✕Probably not a fit
Patients with neck pain from specific pathology, radiculopathy or myelopathy, prior spinal surgery or epidural injections, traumatic spinal cord injury, or progressive neurological deficit are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized interventional study in Karachi will enroll 156 participants aged 18–40 with chronic neck pain and hamstring tightness and randomly assign them to two groups of 78. The experimental group will receive symmetrical scapula–pelvis PNF (PNF-SSPP) exercises while the control group will receive suboccipital muscle inhibition (SMI) plus static hamstring stretching. Outcomes — including pain, disability, neck range of motion, hamstring tightness, head posture, and levator scapulae index — will be measured before treatment, after the first session, and after the 18th session by an independent blinded assessor. Data will be analyzed using repeated-measures ANOVA with an allowance for up to 20% dropout.
Why it matters
Potential benefit: If successful, the PNF approach could reduce neck pain and disability while improving neck mobility and hamstring flexibility.
How similar studies have gone: Previous smaller trials of PNF and manual-release techniques have shown modest gains in neck pain and flexibility, but direct comparisons of these exact protocols are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individual with both male and female gender * Individuals with chronic neck pain (pain for \> 3 month) with hamstring tightness Exclusion Criteria: * Any history related to spinal surgery * Previous administration of epidural injections * Neck pain due to specific pathology * Patients with radiculopathy or myelopathy * Traumatic spinal cord injury * Neck pain associated with progressive neurological deficit or loss of strength
Where it's running
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Sindh Institute of Physical Medicine and Rehabilitation
Karachi, Sindh, Pakistan Recruiting
Study contacts
- Principal investigator: Aftab Ahmed Mirza Baig, PhD — University of Karach
- Study coordinator: Aftab Ahmed Mirza Baig, PhD
- Email: ab.dptrm@gmail.com
- Phone: +923002739920
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.