Shoulder denervation to relieve post-mastectomy radiation shoulder pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial tests thermal radiofrequency (TRF) denervation of individual shoulder nerves to treat shoulder pain following mastectomy and radiotherapy. Eligible participants will receive TRF targeting articular branches of the suprascapular and axillary nerves or receive conservative treatment, with procedures and follow-up at the National Cancer Institute in Cairo. Adults 18–65 years with ASA II–III status and BMI 20–40 are eligible, while people with active infection, recent myocardial infarction, hemodynamic instability, pregnancy, or major psychiatric illness are excluded. Pain levels and shoulder function will be monitored over follow-up to determine the clinical effect of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age (18-65) Years.
2. ASA physical status (II- III).
3. Patients with post mastectomy irradiation shoulder pain.
4. Body mass index (BMI): (20-40) kg/m2.

Exclusion Criteria:

1. Patient refusal.
2. Known sensitivity or contraindication to drugs used in the study.
3. Pregnancy.
4. Recent myocardial infarction.
5. Hemodynamically unstable.
6. Local and systemic sepsis.
7. Psychiatric illness.

Where it's running

• National Cancer institute
  Cairo, Cairo Governorate, Egypt Recruiting

Study contacts

• Study coordinator: suzan Adlan
• Email: dr_s.adlan@hotmail.com
• Phone: +201111068300

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.