Short-term whole-body vibration at different frequencies for people with COPD and healthy adults
Official title: Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Lung Function, Respiratory Function, Upper Extremity Strength and Flexibility, Cardiac Automatic Function and Quality of Life in Healthy and Moderate and Severe Chronic Obstructive Pulmonary Disease (COPD)
Run by National Cheng Kung University · NCT07509606 · Data updated 2026-11-12
This trial tests whether short sessions of whole-body vibration at different frequencies can help breathing, muscle strength, or symptoms in people with COPD and in healthy adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 102 (estimated) |
| Sponsor | National Cheng Kung University Academic / other |
| Locations | 1 site (Tainan) |
| Status | Recruiting |
| Started | April 7, 2025 |
| Main results expected | May 8, 2025 |
| Study ends | December 31, 2027 |
| Registry record updated | April 3, 2026 |
| Trial ID | NCT07509606 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–65 with a clinical diagnosis of COPD or healthy adults without contraindications (no implants, pacemaker, pregnancy, severe comorbidities) who can attend in-person sessions.
✕Probably not a fit
People with pacemakers, recent surgery or wounds, implanted metal hardware, severe cardiovascular disease, pregnancy, uncontrolled serious comorbidities, or those who already exercise regularly are unlikely to benefit or are excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares the immediate (acute) effects of different whole-body vibration (WBV) frequencies applied to both clinically diagnosed COPD patients and healthy adults aged 18–65. Participants who meet inclusion criteria and have no contraindications will receive brief WBV sessions at varying frequencies while researchers measure respiratory function, symptom reports, and muscle performance. The protocol excludes people with implants, pacemakers, recent surgery or wounds, pregnancy, severe cardiovascular disease, uncontrolled comorbidities, or regular high-frequency exercise habits. Outcomes focus on short-term physiological and functional changes rather than long-term rehabilitation effects.
Why it matters
Potential benefit: If successful, the approach could offer a low‑intensity, clinic-based option to temporarily improve breathing, muscle performance, or symptoms for people with COPD.
How similar studies have gone: Prior small studies of WBV in older adults and some COPD cohorts have shown mixed but occasionally positive short-term effects on muscle strength and balance, while strong evidence for respiratory benefits remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Healthy individuals Inclusion Criteria: * No prior experience with whole-body vibration therapy or exposure to vibration-related occupations or sports. * Aged between 18 and 65 years. Exclusion Criteria: * Pregnancy. * Acute thrombosis. * Severe cardiovascular disease. * Presence of a cardiac pacemaker. * Recent wounds due to injury or surgery. * Hip or knee implants. * Acute hernia, intervertebral disc degeneration, or spondylolysis. * Severe diabetes mellitus. * Epilepsy. * Recent infection. * Severe migraine. * Tumor. * Recently implanted intrauterine device, metal pins, or metal plates. * Kidney stones. * Organ failure. * Presence of musculoskeletal, respiratory, neurological, cardiovascular conditions, or any form of acute or chronic pain. * Participation in other research studies concurrently. * Regular exercise habits (engaging in moderate-intensity exercise ≥3 times per week). COPD Inclusion Criteria: * Clinically diagnosed with chronic obstructive pulmonary disease (COPD) and classified as Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II, III, or IV. * No history of hospitalization within the past two months. * No participation in any rehabilitation program within the past two months. * Able to comply with the exercise training program. * Aged 18 years or older. Exclusion Criteria: * Severe respiratory diseases (e.g., bronchiectasis, pulmonary fibrosis, asthma, or tuberculosis). * Current smokers. * Hip or knee implants. * Severe joint disease or history of lower extremity surgery. * History of vitreous hemorrhage. * Dependence on supplemental oxygen. * Severe alcohol abuse (\>80 g/day). * Severe malnutrition (BMI \< 19 kg/m²). * Pregnancy. * Acute thrombosis. * Presence of a cardiac pacemaker. * Recent wounds due to injury or surgery. * Acute hernia, intervertebral disc degeneration, or spondylolysis. * Severe diabetes mellitus. * Epilepsy. * Recent infection. * Severe migraine. * Tumor. * Recently implanted intrauterine device, metal pins, or metal plates. * Kidney stones. * Organ failure. * Altered consciousness or inability to comply with assessments. * Participation in other research studies concurrently
Where it's running
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National Cheng Kung University Hospital
Tainan, Taiwan Recruiting
Study contacts
- Principal investigator: Kun-Ling Tasi, PhD — Department of Physical Therapy, National Cheng Kung University
- Study coordinator: Kun-Ling Tasi, PhD
- Email: Kunlingtsai@mail.ncku.edu.tw
- Phone: 886-6-2353535 Ext.5078
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.