Short term mentalization-based treatment for adolescents with depression

Feasibility and Acceptability of Mentalization-based Treatment for Early Adolescents With Depression: A Short Term Psychotherapy Approach for Patients and Their Families

Not applicable Interventional Universidad de Valparaiso · NCT06252090

This study is testing a new short-term therapy for young teens with mild to moderate depression to see if it helps them and their families feel better together.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages10 Years to 14 Years
SexAll
SponsorUniversidad de Valparaiso Academic / other
Locations1 site (Valparaíso)
Trial IDNCT06252090 on ClinicalTrials.gov

What this trial studies

This pilot trial evaluates the feasibility and acceptability of a short-term mentalization-based treatment (MBT-A) specifically designed for early adolescents diagnosed with mild to moderate depression. The study addresses the pressing need for evidence-based family interventions in adolescent mental health, particularly in the context of rising depression rates exacerbated by the COVID-19 pandemic. By involving families in the therapeutic process, the trial aims to leverage systemic support to enhance treatment outcomes. The study will include 15 families and assess the intervention's practicality and reception among participants.

Who should consider this trial

Good fit: Ideal candidates are early adolescents diagnosed with mild to moderate major depressive disorder who have parental consent to participate.

Not a fit: Patients with autism spectrum disorders, psychosis, bipolar disorder, active suicidal ideation, substance use disorder, or those who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a new, effective approach to managing adolescent depression through family involvement.

How similar studies have performed: While this approach is innovative in the Chilean context, similar mentalization-based treatments have shown promise in other populations, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mild to moderate major depressive disorder (DSM-5-TR and psychiatric interview).
* Written informed consent.
* Presence of at least one legally responsible adult consenting to participate in the therapeutic process.

Exclusion Criteria:

* Diagnoses of autism spectrum disorders
* Psychosis
* Bipolar affective disorder
* Active suicidal ideation
* Substance use disorder.
* Pregnancy

Where this trial is running

Valparaíso

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DepressionAdolescentMentalizationFamilyPsychotherapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.