Shockwave therapy for Peyronie's disease
Official title: Extracorporeal Shockwave Therapy in the Treatment of Peyronie's Disease
Run by Uskudar University · NCT07317297 · Data updated 2026-11-12
This trial will try extracorporeal shockwave therapy to see if it helps men aged 18-65 with stable Peyronie's disease and a palpable penile plaque.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Men only |
| Enrollment | 50 (estimated) |
| Sponsor | Uskudar University Academic / other |
| Locations | 1 site (Baku) |
| Status | Recruiting |
| Started | January 10, 2026 |
| Main results expected | February 15, 2026 |
| Study ends | March 30, 2026 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT07317297 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Men aged 18-65 with Peyronie's disease that has been stable for at least six months and with a palpable penile plaque who have not had prior surgery, needle therapy, or shockwave treatment are ideal candidates.
✕Probably not a fit
Men in the acute inflammatory stage, those with severe erectile dysfunction, prior penile cancer, uncontrolled diabetes, severe coagulopathy, or on anticoagulant therapy are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, prospective trial enrolling men who present to the clinic with stable Peyronie's disease. Eligible participants who provide consent will all receive a standard extracorporeal shockwave therapy protocol. Outcomes will be measured before and after treatment using the International Index of Erectile Function-5 and a short-form quality of life questionnaire. The collected data will be analyzed statistically to determine any changes following the treatment.
Why it matters
Potential benefit: If successful, the treatment could reduce plaque-related curvature and pain and improve erectile function and quality of life.
How similar studies have gone: Previous small studies of extracorporeal shockwave therapy for Peyronie's disease have reported mixed results, with some improvements in pain or plaque but inconsistent effects on curvature and erectile function.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male individuals aged 18-65 years. * Having been diagnosed with Peyronie's Disease that has been stable (without increasing pain and curvature) for at least 6 months. * Presence of palpable penile plaque. Exclusion Criteria: * Acute inflammatory stage (painful, progressive) * Having previously undergone surgery, needle therapy (e.g., Xiaflex), or Extracorporeal Shockwave Therapy for peyronie's disease. * Uncontrolled diabetes, severe coagulopathy, or receiving anticoagulant therapy. * History of penile cancer. * Severe erectile dysfunction. * Patients who are considered unable to comply with the study protocol or who cannot attend follow-up visits.
Where it's running
-
Koreya Serq Tebabeti
Baku, Azerbaijan Recruiting
Study contacts
- Study coordinator: Ömer ŞEVGİN
- Email: omer.sevgin@uskudar.edu.tr
- Phone: +905069787535
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Cord blood platelet-rich plasma plus penile traction versus traction alone for Peyronie's disease
This tests whether adding cord blood platelet-rich plasma injections to penile traction helps men with Peyronie's disease and significant penile curvature.
-
Using shockwave therapy with Xiaflex to treat Peyronie's disease
This study is testing if combining shockwave therapy with a medication called Xiaflex can help men with Peyronie's disease improve their penile curvature better than standard treatment alone.
-
Light-targeted balance training to improve balance and reduce fear of falling
This trial tests whether light-targeted balance training helps people with a history of falls improve balance and functional performance, and feel less afraid of falling, compared with standard balance training.
-
Multichannel neuromuscular stimulation plus core exercise for chronic low back pain
This study tests two multichannel neuromuscular electrical stimulation programs added to a core exercise plan to see if they help adults with chronic non-specific low back pain.
-
Core endurance vs segmental stabilization for low back pain in recreational athletes
This trial tests whether core endurance exercises or segmental stabilization exercises better help recreational athletes with non-specific low back pain.
-
Muscle Energy Technique to improve neck function and range of motion for people with non-specific neck pain
This study will test whether Muscle Energy Technique helps adults aged 18–65 with non-specific neck pain reduce disability and improve neck range of motion.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.