Shock wave therapy to reduce wrist muscle spasticity after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Chronic stroke patients with moderate wrist flexor spasticity will receive radial extracorporeal shock wave therapy in addition to conventional rehabilitation, and outcomes will be compared over short-term follow-up. Clinical spasticity will be measured with the Modified Ashworth Scale while ultrasound strain elastography and echogenicity will provide objective measures of muscle stiffness and tissue quality. The protocol excludes patients with fixed contractures, recent botulinum toxin or phenol injections, multiple strokes, or medical contraindications to ESWT. The study aims to correlate clinical changes with ultrasonographic biomarkers to provide more objective evidence of treatment effect.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 35 and 65 years.
* First-ever stroke episode confirmed by MRI and/or CT scan.
* Clinical diagnosis of hemiplegia.
* More than 6 months post-stroke.
* A Modified Ashworth Scale (MAS) score between 1 and 3 for wrist flexor spasticity.

Exclusion Criteria:

* History of more than one stroke episode
* Stroke onset more than ten years ago
* Stroke onset less than 6 months ago
* Age over 65 (to limit the effects of aging on muscle structure)
* Contraindications for ESWT (e.g., cancer, local tumor or active infection in the treatment area, pregnancy, coagulation disorders, pacemaker or other electronic/metallic implants)
* Severe aphasia or serious communication problems
* Presence of fixed contracture in the wrist
* Patients who have received botulinum toxin or phenol nerve block injections within the last 6 months
* Medically unstable patients (e.g., uncontrolled hypertension, diabetes mellitus, or severe cardiac, hepatic, or renal disease)

Where it's running

• Pamukkale University
  Denizli, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Meltem Güneş Akıncı, Assistant professor
• Email: meltem_aytekin@hotmail.com
• Phone: +905375145590

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.