Shear wave elastography to distinguish obstructive from pregnancy-related hydronephrosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational diagnostic accuracy study enrolling pregnant women (≥12 weeks gestation) with sonographic hydronephrosis and loin pain at Beni-Suef University Hospital. Participants will have clinical and laboratory assessment plus conventional ultrasound and renal cortical stiffness measurements by shear wave elastography, with ten valid measurements per kidney and the median used for analysis. Measurements will be repeated at 2–4 weeks, after any intervention if performed, and at 6–8 weeks postpartum, and the reference diagnosis will be based on clinical course, need for intervention, and postpartum resolution. Diagnostic performance will be quantified using ROC analysis to determine the area under the curve and optimal SWE cut-off values.

Why it matters

Who can join: the full rules

* Inclusion Criteria:

  * Pregnant women ≥12 weeks gestation with Loin Pain.
  * Sonographic evidence of hydronephrosis.
  * Age ≥18 years.
  * Provided informed consent
* Exclusion Criteria:

  * Chronic kidney disease (CKD).
  * Congenital renal anomalies.
  * Pre-eclampsia
  * Poor acoustic window.
  * Contraindication to examination position.

Where it's running

• Beni Suef university hospital
  Banī Suwayf, Beni Suef Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mahmoud Abdallah Mahmoud, lecturer of urology
• Email: mahmoud.abdalla@med.bsu.edu.eg
• Phone: 01155361979

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.