Sexual functioning in trans men during gender affirmation

Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study

Observational Eskisehir Osmangazi University · NCT07131267

This study will see if sexual functioning changes for trans men with gender dysphoria who are receiving medical gender-affirming care in Türkiye.

Quick facts

Study typeObservational
Enrollment52 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorEskisehir Osmangazi University Academic / other
Locations1 site (Eskişehir, Türkiye)
Trial IDNCT07131267 on ClinicalTrials.gov

What this trial studies

This mixed-methods project combines a quantitative survey of 52 trans men using standardized scales with in-depth qualitative interviews of 12 participants about their sexual experiences during gender affirmation. Quantitative measures include the Arizona Sexual Experiences Scale, Sexual Desire Inventory, Utrecht Gender Dysphoria Scale, DASS-21, and the WHOQOL sexual quality of life subscale, along with a sociodemographic and clinical form. The qualitative component uses semi-structured questions to capture personal, cultural, and contextual aspects of sexual functioning during the transition process. Recruitment and data collection occur at Eskişehir Osmangazi University in Türkiye with defined inclusion and exclusion criteria to focus on adult trans men receiving medical support for gender affirmation.

Who should consider this trial

Good fit: Ideal candidates are trans men aged 18–65 diagnosed with gender dysphoria by two physicians who are currently receiving medical support for gender affirmation.

Not a fit: People over 65, those with intellectual disability, dementia, organic mental disorders, systemic illnesses that impair sexual function, or a Clinical Global Impression score above 3 may not benefit from the study findings.

Why it matters

Potential benefit: If successful, the study could clarify how medical gender-affirming care relates to sexual function and help clinicians provide better sexual health support tailored to trans men in Türkiye.

How similar studies have performed: Some international studies have reported changes in sexual functioning after gender-affirming treatment, but this mixed-methods approach is the first of its kind reported in Türkiye.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

18 years or older Diagnosed with gender dysphoria by two different physicians Getting medical support for the gender affirmation process

Exclusion Criteria:

Over 65 years Diagnosed with intellectual disability, dementia, or organic mental disorders Having a systemic disease that negatively impacts sexual function Getting a score above 3 on the Clinical Global Impression Scale

Where this trial is running

Eskişehir, Türkiye

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sexual FunctioningTransgender MenGender Affirmation Surgerysexual functioningtransgender mengender affirmation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.