Sevoflurane versus desflurane for lung protection during robotic abdominal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares two commonly used inhaled anesthetics—sevoflurane and desflurane—in adults aged 18–87 undergoing elective robotic-assisted abdominal procedures with lung-protective mechanical ventilation. Eligible participants have ASA physical status I–III and no significant respiratory, renal, or cardiac comorbidities. Each participant will receive one of the volatile agents during surgery and intraoperative respiratory mechanics and markers of alveolar inflammation will be recorded. Outcomes will be compared between groups at predefined intraoperative and early postoperative time points to determine differences in lung function and inflammatory response.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 to 87 years
* Undergoing elective robotic-assisted abdominal surgery
* ASA physical status I-III

Exclusion Criteria:

* ASA IV or V
* Emergency surgery
* Renal insufficiency
* Clinically significant respiratory disease
* Cardiomyopathy
* Uncontrolled hypertension

Where it's running

• Aretaieion University Hospital
  Athens, Greece Recruiting

Study contacts

• Study coordinator: Aliki Tympa, MD,PhD
• Email: alikitympa@med.uoa.gr
• Phone: 00306955487575

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.