Serum endocan and copeptin levels in preterm babies with respiratory distress

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will measure serum endocan and copeptin on day one of life in preterm neonates (28–36 weeks) diagnosed with respiratory distress syndrome. Blood samples will be analyzed for biomarker concentrations and those levels will be correlated with clinical measures of RDS severity. Infants with IUGR, major congenital or chromosomal anomalies, hypoxic ischemic encephalopathy, maternal chorioamnionitis, infants of diabetic mothers, extreme prematurity (<28 weeks), or PROM >2 hours are excluded. The work is single-center at Tanta University and involves no therapeutic interventions beyond routine clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Prematurity.
* Gestational age between 28 and 36 weeks.
* Suffering from respiratory distress syndrome.

Exclusion Criteria:

* Intrauterine growth restriction (IUGR).
* Hypoxic ischemic encephalopathy.
* Multiple congenital anomalies.
* Chromosomal abnormalities.
* Preterm less than 28 weeks.
* Neonates with a maternal history of chorioamnionitis (early sepsis).
* Infant of diabetic mother.
* Prelabor rupture of membranes (PROM)\> 2 hours.

Where it's running

• Tanta University
  Tanta, El-Gharbia, Egypt Recruiting

Study contacts

• Study coordinator: Asmaa M Elmesiry, MD
• Email: asmaa.elmesery@med.tanta.edu.eg
• Phone: 00201224285567

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.