Serratus posterior superior intercostal block versus serratus anterior plane block for non‑intubated single‑port VATS

Comparison of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block in Uniportal Video-Assisted Thoracoscopic Surgery Without Intubation

Not applicable Interventional Firat University · NCT07440199

We will test whether the serratus posterior superior intercostal block or the serratus anterior plane block gives better pain control and reduces anesthetic use in adults having non‑intubated single‑port VATS.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment70 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorFirat University Academic / other
Locations1 site (Elâzığ)
Trial IDNCT07440199 on ClinicalTrials.gov

What this trial studies

This single‑center interventional comparison enrolls adult patients scheduled for non‑intubated uniportal video‑assisted thoracoscopic surgery (NI‑UniVATS) and assigns them to receive either a serratus anterior plane block (SAPB) or a serratus posterior superior intercostal plane (SPSIP) block. Intraoperative anesthesia requirements, analgesic consumption, and pain scores will be recorded to compare the two fascial plane techniques. The trial excludes patients with prior thoracic surgery, major comorbidities that affect anesthesia or coagulation, and those unable to use the pain rating scale. Procedures and outcome measurement are performed at Fırat University Faculty of Medicine Hospital.

Who should consider this trial

Good fit: Adults aged 18–65 with ASA physical status I–III, BMI under 35 kg/m², able to consent and communicate in Turkish, and scheduled for non‑intubated uniportal VATS are ideal candidates.

Not a fit: Patients with prior thoracic surgery or trauma, widespread pleural adhesions, neuromuscular disease, uncontrolled systemic illness, coagulation disorders, current anticoagulant use, pregnancy, or inability to use the pain scale are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the better block could lower intraoperative anesthetic and postoperative opioid needs, improving pain control and recovery after NI‑UniVATS.

How similar studies have performed: Previous studies have shown SAPB can reduce pain for thoracic procedures, while the serratus posterior superior intercostal plane block is a newer technique with more limited published evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

The study included patients who:

* were aged 18-65 years,
* had an American Society of Anaesthesiologists (ASA) physical status classification of I-III,
* had a body mass index (BMI) \< 35 kg/m²,
* read and signed the informed consent form.

Exclusion Criteria:

Patients;

* Unable to communicate in Turkish or refusing to participate in the study,
* Unable to use the numerical pain rating scale (NRS),
* History of allergy to local anaesthetics or analgesics used in the study,
* Pregnant or breastfeeding,
* History of uncontrolled anxiety disorder or substance dependence,
* Previous thoracic surgery or history of thoracic trauma,
* Widespread pleural adhesions detected during preoperative assessment,
* Neuromuscular or peripheral nervous system disease,
* Diabetes mellitus, hepatic or renal insufficiency, or coagulation disorder,
* Chronic opioid or steroid use,
* Widespread pain syndrome,
* Receiving anticoagulant therapy,
* Patients with infection detected in the area where the block will be applied were excluded.

Where this trial is running

Elâzığ

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions This Study Evaluates the Effects of Different Fascial Plane Blocks on Intraoperative Anesthesia and Analgesic Consumption in Non-intubated VATS ProceduresNIVATSBullectomypleural biopsySerratus Posterior Superior Intercostal BlockSerratus Anterior Plan Block
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.