Sensory-motor integration plus traditional exercises for postmenopausal peripheral neuropathy

The Combination Effect of Sensory-motor Integration in Postmenopausal Polyneuropathy: A Randomized Controlled Trial

Not applicable Interventional New Ismailia National University · NCT07452081

This will see if sensory-motor integration training combined with traditional exercises improves balance and reduces pain in postmenopausal women with diabetic peripheral neuropathy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages45 Years to 55 Years
SexFemale
SponsorNew Ismailia National University Academic / other
Locations2 sites (Ismailia and 1 other locations)
Trial IDNCT07452081 on ClinicalTrials.gov

What this trial studies

This interventional program delivers sensory-motor integration training alongside a regimen of traditional exercises to postmenopausal women with sensory-motor axonal neuropathy, primarily related to type 2 diabetes. Participants must have numbness in the upper and lower limbs for more than four months and will be recruited at sites in Ismailia, Egypt and Amman, Jordan. The study measures outcomes such as balance, pain levels, and functional mobility, with exclusions for prior hysterectomy, active tumors, or current antidepressant use. The protocol compares the combined approach to standard exercise to determine whether adding sensory-motor integration yields greater patient benefit.

Who should consider this trial

Good fit: Ideal candidates are postmenopausal women with type 2 diabetes who have sensory-motor axonal polyneuropathy and persistent numbness in their upper and lower limbs for more than four months, without active tumors, prior hysterectomy, or current antidepressant use.

Not a fit: Patients with neuropathy from other causes, current antidepressant use, active tumors, or a history of hysterectomy would be excluded or less likely to benefit.

Why it matters

Potential benefit: If successful, the combined program could improve balance, reduce neuropathic pain, and lower fall risk in postmenopausal women with diabetic peripheral neuropathy.

How similar studies have performed: Previous trials of exercise and sensorimotor training in diabetic peripheral neuropathy have shown moderate improvements in balance and pain, but combining sensory-motor integration with traditional exercise is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* polyneuropathy pos-tmaneuposal
* Type II Diabetes Mellitus
* Suffering from numbness in upper and lower limbs for more than 4 months

Exclusion Criteria:

* hysterectomy
* tumors
* antidepressant dugs

Where this trial is running

Ismailia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sensory-Motor Axonal Neuropathy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.