Sensor-enabled smartphone support to help teens with poorly controlled asthma
Official title: Optimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control
Run by University of Kansas · NCT07301060 · Data updated 2026-11-12
This project will test whether a sensor-linked app (ReACT) can help 13–17-year-olds with suboptimal asthma control take their inhaled medicines and manage symptoms better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 13 Years to 17 Years |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | University of Kansas Academic / other |
| Locations | 2 sites (Jacksonville, Florida and 1 other locations) |
| Status | Recruiting |
| Started | December 22, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | January 15, 2028 |
| Registry record updated | December 24, 2025 |
| Trial ID | NCT07301060 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are 13–17-year-olds with physician-verified persistent asthma, suboptimal control (ACT ≤19 or guideline-defined symptoms), a daily inhaled corticosteroid compatible with the sensor, who speak English and have their own smartphone.
✕Probably not a fit
Teens without a personal smartphone, with other lung diseases that affect breathing, currently enrolled in another asthma program, or with significant cognitive impairment are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adolescents with persistent asthma and suboptimal control are enrolled and receive a sensor that attaches to their daily inhaled corticosteroid plus a smartphone app that monitors inhaler use and symptoms. The sensor-enabled intervention delivers tailored, in-the-moment prompts and problem-solving support, while a comparison group receives a standard mHealth control condition. The team tracks inhaler adherence, symptom reports, and asthma control over the study period to see if the adaptive, personalized approach improves outcomes. Participants must speak English, have their own smartphone, and meet age and medication compatibility criteria.
Why it matters
Potential benefit: If successful, this approach could improve daily medication use and reduce asthma symptoms and flare-ups for participating teens.
How similar studies have gone: Prior sensor- and app-based asthma programs have generally improved inhaler adherence in adolescents and adults, though impacts on clinical outcomes have been mixed, so the approach is promising but not yet definitively proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria for adolescents are: 1) they are between 13-17 years-old; 2) they have a physician-verified diagnosis of persistent asthma for at least 6 months; 3) they have suboptimal asthma control as defined by national asthma guidelines;5 4) they have a daily inhaled corticosteroid prescription that is compatible with the ReACT sensor; and 5) the adolescent-caregiver dyad speak and read English. Exclusion criteria are: 1) the adolescent is currently involved in an asthma management intervention beyond usual care; 2) the adolescent has a comorbid chronic health condition that may impact lung function (e.g., cystic fibrosis); 3) the adolescent has significant cognitive impairment or developmental delay that interferes with study completion, and 4) the adolescent does not have their own smart phone. Consistent with national asthma guidelines, we define suboptimal as control as a score of ≤19 on the Asthma Control Test (ACT) or by endorsing one or more of the following symptoms of on \>4 days in the past 2 weeks: (a) use of any short-acting beta-agonist medication, (b) experiencing asthma symptoms (i.e., wheezing, tightness of chest, coughing) during the day or night, (c) nighttime awakening due to asthma, or (d) activity limitation or school absence due to asthma.
Where it's running
-
Nemours Children's Health
Jacksonville, Florida, United States Recruiting -
University of Kanas
Lawrence, Kansas, United States Recruiting
Study contacts
- Study coordinator: Christopher C. Cushing, Ph.D.
- Email: christopher.cushing@ku.edu
- Phone: 785-864-0713
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
IOS-based platform to screen, diagnose, and manage COPD and asthma
This study tests an Impulse Oscillometry system to screen for and diagnose COPD and asthma and to help predict flare-ups over about a year, involving adults in China.
-
REACH: Resources and Education to Help Kids with Asthma in School
A service model called REACH will try to improve school-based asthma care by coordinating care between healthcare, school, and home for children with asthma.
-
Beclometasone Dipropionate and Formoterol inhalation combo vs FOSTER in adults with asthma
This Phase 3 trial tests whether a beclometasone formoterol inhalation combo works as well or better than FOSTER for adults with asthma.
-
Test of SKB575 in adults with asthma
This study tests whether SKB575 helps people with asthma compared to a placebo.
-
KT-621 long-term safety and efficacy in asthma patients previously in KT-621 study
This phase 2b study tests KT-621 in people with asthma who finished a prior KT-621 study to see if long-term treatment is safe and helpful.
-
Dog-allergy immunotherapy with Alutard SQ Dog in Swedish practice
This study tests whether Alutard SQ Dog immunotherapy helps adults with moderate-to-severe dog allergy when used in real-world Swedish care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.