Semi-solid foods and swallowing gels to help people who have trouble swallowing pills.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses flexible endoscopic evaluation of swallowing (FEES) as the diagnostic gold standard to document how often medication-related swallowing problems occur in people with dysphagia-associated diseases and in healthy controls. Participants will attempt medication intake with different consistencies, including semi-solid carriers and a commercially available swallowing gel, while clinicians record safety and bolus transport findings. The primary goals are to measure the prevalence of medication dysphagia and to compare whether alternative consistencies reduce penetration, aspiration, or residue during swallowing. Results aim to inform practical recommendations for safer medication administration in affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients:

Adults with a dysphagia-associated disease (neurovascular, neurodegenerative, neuroinflammatory, or neuromuscular disorders; in other centers also ENT-related diseases), for whom FEES is clinically indicated.

Capable of providing informed consent and cognitively able to follow the study protocol.

Healthy Controls Adults without any dysphagia-associated disease (no neurovascular, neurodegenerative, neuroinflammatory, or neuromuscular disorders; no ENT-related diseases with structural abnormalities of the oropharynx or esophagus).

Capable of providing informed consent and cognitively able to follow the study protocol.

Exclusion Criteria:

No additional exclusion criteria beyond those specified in the inclusion criteria.

Where it's running

• University Hospital Düsseldorf
  Düsseldorf, North Rhine-Westphalia, Germany Recruiting
• University Hospital Münster
  Münster, North Rhine-Westphalia, Germany Recruiting
• Hospital Osnabrücl
  Onsabrück, Germany Recruiting

Study contacts

• Study coordinator: Bendix FEES Labeit, MD
• Email: Bendix.Labeit@med.uni-duesseldorf.de
• Phone: 0049211 8117887

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.