Self-triage in breast cancer screening using digital mammography and AI

Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images NOTE: Note, This is One Study Under Study ID 386408 Project 1: Radiologist Studies

Not applicable Interventional Brigham and Women's Hospital · NCT05960188

This study is testing if radiologists can accurately decide which breast cancer screening cases are normal using just 2D digital mammography images, with some help from AI, to make the screening process faster and easier.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorBrigham and Women's Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT05960188 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility of radiologists triaging breast cancer screening cases based solely on 2D digital mammography images, potentially aided by artificial intelligence (AI). The goal is to determine how accurately radiologists can identify normal cases without reviewing more complex 3D digital tomosynthesis images, thereby streamlining the screening process. The study will assess radiologists' willingness to rely on their judgment and AI opinions for case dismissal. This approach aims to enhance efficiency in breast cancer screening while ensuring that no cancers are overlooked.

Who should consider this trial

Good fit: Ideal candidates for this study are radiologists or radiology trainees with experience in reading mammography.

Not a fit: Patients with visual acuity less than 20/25 may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the time and resources needed for breast cancer screening, improving patient throughput and potentially leading to earlier detection.

How similar studies have performed: While the use of AI in radiology is a growing field, this specific approach to triaging cases based on 2D images is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Must be Radiologists or radiology trainees
* some experience reading mammography.

Exclusion Criteria:

* acuity less than 20/25 with correction

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer ScreeningMammographyDigital Breast TomosynthesisArtificial IntelligenceRadiologyMedical Image Perception
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.