Self Assembled Skin Substitute for treating severe burn wounds

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the safety and effectiveness of Self Assembled Skin Substitute (SASS) grafts as a permanent solution for full-thickness burn wounds that require coverage, particularly when donor sites for traditional skin grafts are limited. The study involves patients with deep second or third-degree burns covering a significant portion of their body. Participants will receive SASS grafts to assess their potential as a viable alternative to conventional treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Deep second degree burns or third degree burns over 50% TBSA (Total body surface area) at time of recruitment or as determined by the surgeon;
* Limited availability of donor sites for autografts;
* Consent obtained by the participant or by the appropriate representative in case of inapt prospective participants or minors.

Exclusion Criteria:

* Skin grafting needed only on the face, hands, feet, ears or genital area;
* Connective tissue diseases;
* Hypersensitivity to bovine proteins;
* Coagulation disorders prior being burned;
* Immunodeficiency prior being burned;
* Uncontrolled diabetes prior being burned;
* Permanent wound coverage before SASS grafts are ready;

Where it's running

• Foothill Medcial Centre
  Calgary, Alberta, Canada Recruiting
• Mackenzie Health Science's Centre
  Edmonton, Alberta, Canada Recruiting
• Vancouver General Hospital
  Vancouver, British Columbia, Canada Recruiting
• BC Children's Hospital Plastic Surgery Clinic
  Vancouver, British Columbia, Canada Recruiting
• Winnipeg Health Science Center
  Winnipeg, Manitoba, Canada Recruiting
• Hospital for Sick Children (Sickkids)
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Veronique J Moulin, PhD — CHU de Quebec
• Study coordinator: Veronique J Moulin, PhD
• Email: veronique.moulin@fmed.ulaval.ca
• Phone: 418-525-4444

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.