Seeing if healthy foods reduce brain inflammation and improve eating habits in kids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project combines MRI imaging and feeding interventions to examine links between nutritious foods and hypothalamic inflammation in children. One component gathers caregiver and child input through in-person focus groups to shape acceptable feeding strategies. Another component enrolls children aged 9–11 with BMI in the overweight range for MRI scans before and after dietary intervention to measure changes in brain inflammation. A parallel arm examines feasibility and acceptability of the food-feeding approaches in families qualifying for free or reduced-cost lunch.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Study1: Adult caregiver and Child age 9-11y. Willing to come to in-person focus group
* Study 2: Age 9-11y, BMI ≥85th and ≤95th percentile for age and sex
* Study 3:Adult caregiver with child who qualify for free or reduced-cost lunch in WA State. Child age 9-11y and with overweight.

Exclusion Criteria (study 1 child participants and study 3 criteria for children of adult participants):

* Significant health conditions including type 2 diabetes
* History of major weight loss or eating disorder
* Current use of medications known to alter appetite or body weight (e.g., stimulants for ADHD)
* Documented cognitive disorder
* Severe food allergies, vegetarian, or vegan (Study 1 only)
* Unable to make the session date

Exclusion Criteria (study 2, child participants):

* Significant health conditions including type 2 diabetes
* History of major weight loss or eating disorder
* Current use of medications known to alter appetite or body weight (e.g., stimulants for ADHD)
* Documented cognitive disorder
* MRI contraindication (e.g., braces, claustrophobia)
* Weight \>330 pounds (MRI limit)
* Severe food allergies, vegetarian, or vegan
* Currently in formal weight loss program

Where it's running

• University of Washington
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Ellen Schur, MD — University of Washington
• Study coordinator: BRIDGE Study
• Email: bridge-study@uw.edu
• Phone: 206 616-6360

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.