Seawater nasal spray with essential oils for short-term relief of blocked nose from acute rhinitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a post-market observational investigation of a mechanical decongestant seawater nasal spray enriched with essential oils, conducted over a seven-day period. Patients aged 12 and older with acute rhinitis and nasal obstruction from infectious or allergic causes will use the marketed spray and complete questionnaires on symptoms and tolerability. No experimental drugs are given; outcomes and any adverse events are collected in a real-world pharmacy setting at participating sites. Safety monitoring focuses on reported side effects and contraindications such as known hypersensitivity to the product ingredients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Patient ≥ 12 years,
* 2\. Patient with acute rhinitis associated with nasal obstruction during infectious episodes such as rhynopharyngitis (cold), rhinosinusitis, or during non-infectious episodes as allergic rhinitis,
* 3\. a. Informed adult patient who has given written consent prior to any study specific procedure,
* b. Informed minor patients who has given assent and whose legal guardians have given written consent prior to any study specific procedure,
* 4\. Patient able to meet the study requirements (questionnaire completion),
* 5\. Patient affiliated to a social security scheme.

Exclusion Criteria:

* 1\. Patient who does not want to participate to the clinical investigation,
* 2\. Hypersensitivity to seawater and/or known allergies to any of the ingredients of the spray,
* 3\. A child with a history of febrile convulsions,
* 4\. Diseases leading to respiratory insufficiency,
* 5\. Patient suffering from nasal deformity or nasal polyps leading to chronic nasal obstruction,
* 6\. Patient on local ans systemic vasoconstrictors, local and systemic corticosteroids and antihistamines, non-steroidal anti-inflammatory (NSAIDs), antibiotics and local antiseptics,
* 7\. Concomitant use of other nasal sprays, essential oils for local nasal use and nsal cream or gel,
* 8\. Patient under guardianship, curatorship of safeguard of justice.

Where it's running

• Pharmacie de la Guérinière
  Caen, France Recruiting
• Pharmacie du Pont Saint Jean
  Bayeux, France Not yet recruiting
• Pharmacie de la Force
  La Force, France Not yet recruiting

Study contacts

• Study coordinator: Léa RADDAY
• Email: lradday@labogilbert.fr
• Phone: +33 (0)2 31 47 16 61

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Assessment of a decongestant seawater spray with essential oils for nasal obstruction

  This study is testing a new seawater spray with essential oils to see if it helps people aged 12 and older who have nasal congestion from colds or allergies breathe easier.

  Recruiting at 3 sites Laboratoires Gilbert · Blainville-sur-Orne and 4 other locations · NCT05494346

• Post-marketing follow-up of four devices for acute viral rhinitis and related conditions

  This study tests four medical devices (NS, NHE, NHG, and PIR) in real-life use to see if they are safe, tolerated, and helpful for people with acute viral rhinitis, rhinosinusitis, or rhinopharyngitis.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT07383493

• Mannan-Conjugated Allergoids for House Dust M mite Allergy

  A new treatment named EP-088_MM09 is being tested to see if it can reduce nasal and eye allergy symptoms (and possibly asthma) in people aged 12 to 65 who are allergic to house dust mites, compared with a placebo.

  Recruiting at 2 sites Phase 3 Inmunotek S.L. · Covilha, Castelo Branco District and 15 other locations · NCT07904195

• Mannan-conjugated Allergoids for House Dust Mite Allergy

  A new treatment called EP-088_MM09 is being tested to see if it can reduce allergy symptoms in people with house dust mite–related nasal allergy, with or without mild asthma.

  Recruiting at 4 sites Phase 3 Inmunotek S.L. · Coimbra and 15 other locations · NCT07904052

• Pharyngeal Mucosal Conditioning to Prevent Postoperative Sore Throat in Septoplasty Patients with Severe Nasal Obstruction

  This trial tests whether preoperative nebulized saline and a lubricating gel on the breathing tube can lower sore throat after septoplasty in patients with severe nasal blockage.

  Recruiting Mansoura University · Buraidah, Al-Qassim Region · NCT07870252

• Dog-allergy immunotherapy with Alutard SQ Dog in Swedish practice

  This study tests whether Alutard SQ Dog immunotherapy helps adults with moderate-to-severe dog allergy when used in real-world Swedish care.

  Recruiting at 2 sites Phase 4 Karolinska Institutet · Lund, Skåne County and 1 other locations · NCT07651891

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.