Screening for resistant bacteria in hospitalized patients
Prevalence of Rectal Carriage of Carbapenemase Producing-Enterobacteriaceae on Admission to a French University Teaching Hospital
This study is testing how common certain drug-resistant bacteria are in patients admitted to the hospital to help improve infection control and treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1195 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris, Île-de-France Region) |
| Trial ID | NCT05798351 on ClinicalTrials.gov |
What this trial studies
This observational study aims to determine the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) and extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLE) in patients admitted to Bichat - Claude-Bernard Hospital. It will involve systematic screening of rectal carriage of these resistant bacteria upon hospital admission, focusing on identifying risk factors associated with CPE carriage. The findings will help inform infection control measures and guide antibiotic therapy for affected patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 years and older who are admitted to medical, surgical, obstetrical, or intensive care units at Bichat - Claude-Bernard Hospital.
Not a fit: Patients who have been hospitalized at Bichat - Claude-Bernard Hospital for more than 72 hours prior to inclusion may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance early detection and management of antibiotic-resistant infections in hospitalized patients.
How similar studies have performed: While the study focuses on a specific hospital setting, similar approaches to screening for antibiotic-resistant bacteria have shown promise in other healthcare environments.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria * Age ≥ 18 years * Admission to a medical, surgical, obstetrical or intensive care unit at Bichat - Claude-Bernard Hospital in the previous 72 hours * No objection to participating in the study Non-inclusion criteria * Admission to Bichat - Claude-Bernard Hospital \> 72 hours before inclusion * Readmission to the same ward after discharge * Hospitalization in a rehabilitation unit or a long-stay unit * Non affiliation to social security * Patient under legal protection
Where this trial is running
Paris, Île-de-France Region
- Bichat Hospital — Paris, Île-de-France Region, France (Recruiting)
Study contacts
- Principal investigator: Solen Kernéis, MD - PhD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Solen Kernéis, MD - PhD
- Email: solen.kerneis@aphp.fr
- Phone: 33140256199
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.