Screening for Ischemic Stroke in the Posterior Circulation Using MRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness of preoperative magnetic resonance imaging (MRI) in selecting patients with posterior circulation ischemic stroke who are likely to benefit from mechanical thrombectomy. It focuses on the pons-midbrain-medulla index (PMMI) to assess the degree of ischemia and correlate it with clinical outcomes 90 days post-surgery. By analyzing MRI images, the study aims to improve patient selection for endovascular thrombectomy, potentially leading to better recovery outcomes. The study is conducted as a multicenter, prospective cohort analysis involving several hospitals in Tianjin.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient admitted from Jun. 1st 2019 to Jan. 1st 2029;
2. Patients with acute ischemic stroke recently；
3. Symptoms persisted at admission, and MRI (including DWI) confirmed acute ischemic vertebrobasilar artery occlusion in the posterior circulation:（single right or left intracranial branch of vertebral artery occlusion ; single basilar occlusion ; both two vertebral arterys and basilar artery）；

Exclusion Criteria:

1.Patiens can not meet the MRI examination conditions(with absolute and relative contraindications).

Where it's running

• Tianjin Medical University General Hospital
  Tianjin, Tianjin Municipality, China Recruiting
• The Sencond Hospital of Tianjin Medical University
  Tianjin, Tianjin Municipality, China Recruiting
• Tianjin Huanhu Hospital
  Tianjin, Tianjin Municipality, China Recruiting
• Beijing University Binhai Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Ming Wei, PhD
• Email: drweiming@163.com
• Phone: 13502182903

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.