Screening for Deep Vein Thrombosis in ICU Patients
Ultrasound Screening for Asymptomatic Deep Vein Thrombosis in Critically Ill Patient: a Multicenter Trial
NA · University Of Perugia · NCT06246604
This study is testing if using ultrasound to check for blood clots in the legs can help ICU patients get better care and avoid serious complications.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 1300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Of Perugia (other) |
| Locations | 5 sites (Città Di Castello and 4 other locations) |
| Trial ID | NCT06246604 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of active ultrasound screening for deep vein thrombosis (DVT) in patients admitted to the Intensive Care Unit (ICU) for more than 96 hours. The research is based on previous findings that suggest early detection of DVT can lead to better management and potentially improve patient outcomes. By identifying DVTs earlier, the study hopes to reduce the incidence of more severe proximal DVTs, which are associated with worse long-term prognoses. The intervention involves standard-of-care alongside ultrasound screening for lower limb DVT.
Who should consider this trial
Good fit: Ideal candidates for this study are patients admitted to the ICU with a length of stay exceeding 96 hours.
Not a fit: Patients who are pregnant, have a SARS-CoV-2 infection, or have established DVT or pulmonary embolism at admission will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of severe DVTs and improve both in-hospital and long-term outcomes for critically ill patients.
How similar studies have performed: Previous studies have indicated that ultrasound screening can effectively reduce the incidence of DVT, suggesting that this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * any patient admitted to ICU with a length-of-stay in ICU \>96 hours Exclusion Criteria: * pregnancy * SARS-CoV-2 infection * established DVT or pulmonary embolism at admission * established coagulation disorder * presence of inferior vena cava filter at the admission * admission from the ICU of another hospital
Where this trial is running
Città Di Castello and 4 other locations
- Azienda Sanitaria Locale N.1 dell'Umbria — Città Di Castello, Italy (RECRUITING)
- Azienda Sanitaria Locale N.2 dell'Umbria — Foligno, Italy (RECRUITING)
- Azienda Sanitaria Locale N.1 dell'Umbria — Gubbio, Italy (RECRUITING)
- Azienda Ospedaliera di Perugia — Perugia, Italy (RECRUITING)
- Azienda Ospedaliera di Terni — Terni, Italy (RECRUITING)
Study contacts
- Study coordinator: Leonella Pasqualini, MD
- Email: leonella.pasqualini@unipg.it
- Phone: +390755784030
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Deep Vein Thrombosis