Screening for cervical pre-cancer and cancer prevention in South African women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of cervical pre-cancer and cancer among women in South Africa, where cervical cancer remains a significant health issue. It focuses on improving screening methods, particularly through the use of HPV testing, to enhance early detection and prevention strategies. Participants will undergo cervical cytology screening, colposcopy, and LLETZ procedures as necessary, with the goal of identifying undiagnosed cases of cervical disease. The study seeks to gather data that could inform better screening practices and ultimately reduce cervical cancer incidence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Informed consent accepted and signed
* Health seeking behaviour or request for a cervical cancer screening test
* Willing and able to receive test result by automated text message or clinic visit

Exclusion Criteria:

* Current pregnancy
* Hysterectomy
* Current or previous treatment for gynaecological cancer
* Hesitant or unable to undergo screening and treatment if indicated

Where it's running

• Steve Biko Academic Hospital
  Pretoria, Gauteng, South Africa Recruiting

Study contacts

• Principal investigator: Greta D Dreyer, PhD — University of Pretoria
• Study coordinator: Greta Dreyer, PhD
• Email: greta.dreyer@up.ac.za
• Phone: +(27) 12 354 3900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Urine HPV testing for cervical cancer screening in HIV-infected women in South Africa

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  Recruiting UNC Lineberger Comprehensive Cancer Center · Westdene, Johannesburg · NCT05413798

• Evaluating a 9-valent HPV vaccine in healthy Chinese women

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  Recruiting Phase 3 Shanghai Bovax Biotechnology Co., Ltd. · Liuzhou, Guangxi · NCT04422366

• Cervical screening and care options for women living with HIV who test positive for high-risk HPV

  This study tests different ways to screen and manage high-risk HPV in women with HIV to see what might work best for them.

  Recruiting University of California, San Diego · Nairobi · NCT07925307

• Hydrogel spacer to protect the rectum during cervical cancer radiotherapy

  This study tests whether placing an absorbable hydrogel spacer between the cervix/vagina and rectum before definitive radiotherapy can reduce rectal radiation exposure for women with cervical cancer.

  Recruiting Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT07904182

• How cinema sessions during chemotherapy might help cervical cancer patients

  We’re testing if watching films during chemotherapy helps cervical cancer patients feel less anxious and improve quality of life.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT07902180

• One-Finger Technique to identify the left upper ureter during para-aortic lymphadenectomy

  This study tests a new surgical method to help surgeons find the left upper ureter during open para-aortic lymphadenectomy in women with gynecologic cancers.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07895212

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.