Saline-enhanced ultrasound to detect pelvic adhesions in infertile women
Official title: Role of Saline Infusion Sonohysterography in Detection of Pelvic Adhesions in Infertile Women
Run by Sohag University · NCT07416591 · Data updated 2026-11-12
This test sees if saline infusion sonohysterography (SIS) can detect pelvic adhesions in women aged 18–45 who are experiencing infertility.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Sohag University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Status | Recruiting |
| Started | October 15, 2025 |
| Main results expected | October 15, 2026 |
| Study ends | October 15, 2026 |
| Registry record updated | February 18, 2026 |
| Trial ID | NCT07416591 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18–45 with infertility suspected to involve pelvic adhesions, normal ovulatory function, and normal partner semen analysis are the intended participants.
✕Probably not a fit
Patients with active pelvic infection, abnormal vaginal bleeding, cervical stenosis, congenital uterine anomalies, pelvic malignancy, or those who do not meet the age or fertility-criteria are unlikely to be eligible or to benefit from this procedure.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants will undergo saline infusion sonohysterography (SIS), a procedure that introduces sterile saline into the uterine cavity while performing ultrasound to improve visualization of the endometrium, uterine cavity, adnexa, and tubal patency. The trial enrolls women aged 18–45 with infertility suspected to be related to pelvic adhesions, normal ovulatory function, and normal partner semen analysis, and excludes those with active pelvic infection, abnormal vaginal bleeding, cervical stenosis, congenital uterine anomalies, or pelvic malignancy. SIS is minimally invasive, avoids ionizing radiation compared with hysterosalpingography, and is generally well tolerated. The procedure is being offered at Sohag University Hospital as a diagnostic approach to better identify adhesion-related causes of infertility.
Why it matters
Potential benefit: If successful, SIS could provide a less invasive, radiation-free way to identify pelvic adhesions and help guide fertility treatment decisions.
How similar studies have gone: Previous studies have found SIS useful for detecting intrauterine abnormalities and tubal patency, although its specific performance for identifying pelvic adhesions is less well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * infertile women aged 18-45yr Patient suspected to have pelvic Adhesions Women with normal ovulatory function and normal husband semen analysis Exclusion Criteria: * active pelvic infection or abnormal vaginal bleeding Pt with cervical stenosis Congenital uterine mullerian anomalies Pt with pelvic malignancy
Where it's running
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Sohag University hospital
Sohag, Sohag Governorate, Egypt Recruiting
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.