Saline-enhanced ultrasound to detect pelvic adhesions in infertile women
Role of Saline Infusion Sonohysterography in Detection of Pelvic Adhesions in Infertile Women
This test sees if saline infusion sonohysterography (SIS) can detect pelvic adhesions in women aged 18–45 who are experiencing infertility.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Sohag University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Trial ID | NCT07416591 on ClinicalTrials.gov |
What this trial studies
Participants will undergo saline infusion sonohysterography (SIS), a procedure that introduces sterile saline into the uterine cavity while performing ultrasound to improve visualization of the endometrium, uterine cavity, adnexa, and tubal patency. The trial enrolls women aged 18–45 with infertility suspected to be related to pelvic adhesions, normal ovulatory function, and normal partner semen analysis, and excludes those with active pelvic infection, abnormal vaginal bleeding, cervical stenosis, congenital uterine anomalies, or pelvic malignancy. SIS is minimally invasive, avoids ionizing radiation compared with hysterosalpingography, and is generally well tolerated. The procedure is being offered at Sohag University Hospital as a diagnostic approach to better identify adhesion-related causes of infertility.
Who should consider this trial
Good fit: Women aged 18–45 with infertility suspected to involve pelvic adhesions, normal ovulatory function, and normal partner semen analysis are the intended participants.
Not a fit: Patients with active pelvic infection, abnormal vaginal bleeding, cervical stenosis, congenital uterine anomalies, pelvic malignancy, or those who do not meet the age or fertility-criteria are unlikely to be eligible or to benefit from this procedure.
Why it matters
Potential benefit: If successful, SIS could provide a less invasive, radiation-free way to identify pelvic adhesions and help guide fertility treatment decisions.
How similar studies have performed: Previous studies have found SIS useful for detecting intrauterine abnormalities and tubal patency, although its specific performance for identifying pelvic adhesions is less well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * infertile women aged 18-45yr Patient suspected to have pelvic Adhesions Women with normal ovulatory function and normal husband semen analysis Exclusion Criteria: * active pelvic infection or abnormal vaginal bleeding Pt with cervical stenosis Congenital uterine mullerian anomalies Pt with pelvic malignancy
Where this trial is running
Sohag, Sohag Governorate
- Sohag University hospital — Sohag, Sohag Governorate, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.