Rotating a stylet-loaded endotracheal tube before intubation to reduce throat soreness
Official title: Endotracheal Tube (ETT) 180: Stylet-loaded Endotracheal Tube Rotation Before Insertion to Decrease the Risk of Postoperative Sore Throat: a Randomized Double-Blind Prospective Trial.
Run by Ohio State University · NCT06231342 · Data updated 2026-11-12
This study is testing if turning a special type of breathing tube before putting it in can help reduce throat soreness after surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 357 (estimated) |
| Sponsor | Ohio State University Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Status | Recruiting |
| Started | May 31, 2023 |
| Main results expected | May 31, 2027 |
| Study ends | May 31, 2027 |
| Registry record updated | April 29, 2026 |
| Trial ID | NCT06231342 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 to 90 who are ASA I-III and undergoing general anesthesia with ETT placement.
✕Probably not a fit
Patients with a history of difficult airways, those requiring intensive care, or undergoing surgeries involving the pharynx or larynx may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to determine if rotating a stylet-loaded endotracheal tube (ETT) 180 degrees before insertion can reduce the incidence of postoperative throat soreness compared to standard intubation techniques. Patients will be randomized into groups, and experienced anesthesiologists will perform the intubations using specific equipment and techniques. Data will be collected postoperatively to assess throat soreness, ensuring that both patients and investigators are blinded to the intervention.
Why it matters
Potential benefit: If successful, this approach could lead to less postoperative throat soreness for patients undergoing general anesthesia.
How similar studies have gone: While this specific approach is novel, similar studies have explored techniques to reduce postoperative complications, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I - III * Ambulatory patients undergoing general anesthesia with an Endotracheal Tube (ETT) placement * Admitted patients undergoing general anesthesia an Endotracheal Tube (ETT) placement * Age \> 18 and \< 90 years old * BMI \< 50 Exclusion criteria: * Age \< 18 years old or age \> 90 years old * Pregnant women * Prisoners * Any surgery involving the pharynx, larynx, vocal cords, trachea that will create confounding factors related to postoperative sore throat * History of difficult airway * Critically ill patients requiring intensive care
Where it's running
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The Ohio State University Wexner Medical Center
Columbus, Ohio, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.