Robotic bronchoscopic ablation for small peripheral lung tumors
Official title: Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry
Run by M.D. Anderson Cancer Center · NCT06840288 · Data updated 2026-11-12
This registry collects information on people with primary or metastatic peripheral lung tumors who have robotic-assisted bronchoscopic ablation to see how safe the procedure is and how well it controls tumors.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | February 19, 2025 |
| Main results expected | December 31, 2034 |
| Study ends | December 31, 2036 |
| Registry record updated | October 9, 2026 |
| Trial ID | NCT06840288 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people with peripheral lung tumors (primary lung cancer or metastases) who have undergone or are scheduled to undergo robotic-assisted bronchoscopic ablation with a completed ablation procedure.
✕Probably not a fit
Patients whose planned bronchoscopic ablations were aborted before completion, those with non-peripheral (central) tumors, or patients not treated with robotic bronchoscopic ablation are unlikely to benefit directly from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center observational registry at M.D. Anderson collects clinical, procedural, radiographic, and outcomes data from participants with known lung cancer or lung metastases who undergo robotic-assisted bronchoscopic ablation of peripheral tumors. It aggregates intra-operative, peri-operative, and long-term safety outcomes including bleeding, pneumothorax, and infection, and tracks oncologic outcomes such as local tumor progression by RECIST, LTPFS, PFS, DSS, and OS. The registry also analyzes serial imaging to characterize radiographic evolution of ablated lesions and evaluates tumor- and patient-level risk factors associated with safety and oncologic results. Procedures in which bronchoscopic ablation was planned but aborted for technical reasons are excluded from analysis.
Why it matters
Potential benefit: If successful, the registry could help doctors better understand the safety and effectiveness of robotic bronchoscopic ablation and improve patient selection and follow-up care.
How similar studies have gone: Percutaneous thermal ablation has established evidence, while robotic-assisted bronchoscopic ablation is a newer approach with limited but growing early data supporting feasibility and safety.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients with peripheral lung tumors (primary or metastatic) that have been or will be ablated via robotic bronchoscopy. Exclusion Criteria: Patients with planned bronchoscopic ablations of peripheral lung tumors that were aborted for technical reasons (ablation was not completed).
Where it's running
-
MD Anderson Cancer Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Roberto F Casal, MD — Prinicipal Investigator
- Study coordinator: Roberto F Casal, MD
- Email: rfcasal@mdanderson.org
- Phone: (713) 792-6238
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Community- or home-based exercise for adults with weakened heart or lungs
This test will see if an eight-week, community- or home-based exercise program can improve heart and lung function in adults 18–85 with reduced cardiopulmonary fitness.
-
Register of patients with thoracic tumors
This study is collecting information from patients with lung cancer and other chest tumors to see how different treatments can be tailored to help them feel better and live longer.
-
Preventing heart problems in overweight/obese young sarcoma survivors with tirzepatide
This feasibility study tests whether tirzepatide can be safely given to overweight or obese young adults (18–39) who have completed doxorubicin for soft tissue or bone sarcoma to see if it’s feasible to use in the first year after therapy.
-
Predicting lymphedema risk in inflammatory breast cancer patients using preoperative body impedance analysis
This study tests whether a preoperative bioimpedance test can help identify IBC patients who are at risk for developing lymphedema.
-
Precision genomic testing to guide first-line LBCL treatment readiness
Doctors will see if a tumor genomic test can help tailor first-line treatment for adults with LBCL by the start of the second cycle of standard therapy.
-
Using Apple Vision Pro in image-guided procedures
This study tests whether the Apple Vision Pro can be used during CT-guided biopsy procedures to help with imaging and guidance.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.