Clinical trial Recruiting at 1 site Observational Ages 18 and up

Robotic bronchoscopic ablation for small peripheral lung tumors

Official title: Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry

Run by M.D. Anderson Cancer Center · NCT06840288 · Data updated 2026-11-12

This registry collects information on people with primary or metastatic peripheral lung tumors who have robotic-assisted bronchoscopic ablation to see how safe the procedure is and how well it controls tumors.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment250 (estimated)
SponsorM.D. Anderson Cancer Center
Academic / other
Locations1 site (Houston, Texas)
StatusRecruiting
StartedFebruary 19, 2025
Main results expectedDecember 31, 2034
Study endsDecember 31, 2036
Registry record updatedOctober 9, 2026
Trial IDNCT06840288 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people with peripheral lung tumors (primary lung cancer or metastases) who have undergone or are scheduled to undergo robotic-assisted bronchoscopic ablation with a completed ablation procedure.

Probably not a fit

Patients whose planned bronchoscopic ablations were aborted before completion, those with non-peripheral (central) tumors, or patients not treated with robotic bronchoscopic ablation are unlikely to benefit directly from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center observational registry at M.D. Anderson collects clinical, procedural, radiographic, and outcomes data from participants with known lung cancer or lung metastases who undergo robotic-assisted bronchoscopic ablation of peripheral tumors. It aggregates intra-operative, peri-operative, and long-term safety outcomes including bleeding, pneumothorax, and infection, and tracks oncologic outcomes such as local tumor progression by RECIST, LTPFS, PFS, DSS, and OS. The registry also analyzes serial imaging to characterize radiographic evolution of ablated lesions and evaluates tumor- and patient-level risk factors associated with safety and oncologic results. Procedures in which bronchoscopic ablation was planned but aborted for technical reasons are excluded from analysis.

Why it matters

Potential benefit: If successful, the registry could help doctors better understand the safety and effectiveness of robotic bronchoscopic ablation and improve patient selection and follow-up care.

How similar studies have gone: Percutaneous thermal ablation has established evidence, while robotic-assisted bronchoscopic ablation is a newer approach with limited but growing early data supporting feasibility and safety.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients with peripheral lung tumors (primary or metastatic) that have been or will be ablated via robotic bronchoscopy.

Exclusion Criteria:

Patients with planned bronchoscopic ablations of peripheral lung tumors that were aborted for technical reasons (ablation was not completed).

Where it's running

  • MD Anderson Cancer Center
    Houston, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.