Robot-assisted training for spinal muscular atrophy
Evaluation of a Portable Isokinetic Knee Training Device for Quadriceps Rehabilitation in Children With SMA
This study is testing whether a special robot-assisted training can help people with spinal muscular atrophy get stronger and improve their movement over time.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 13 (estimated) |
| Ages | 6 Years to 12 Years |
| Sex | All |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06648486 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the long-term effects of isokinetic rehabilitation training in patients with spinal muscular atrophy (SMA). Participants will engage in isokinetic training using a portable device that operates at a fixed angular velocity. The study aims to determine whether this training can improve muscle strength and functional recovery in SMA patients over an extended rehabilitation period. Assessments will be conducted to measure muscle strength and overall functional improvement throughout the training.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 5-30 years diagnosed with spinal muscular atrophy.
Not a fit: Patients with other major diseases or conditions, or those unable to participate fully, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance muscle strength and functional abilities in patients with spinal muscular atrophy.
How similar studies have performed: While similar approaches have been explored, this specific application of robot-assisted isokinetic training in SMA is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age range: 6-12 years old. 2. Diagnosed with Type II Spinal Muscular Atrophy (SMA). Exclusion Criteria: 1. Participants with severe comorbidities, implanted medical devices preventing MRI or claustrophobia were excluded from the study. 2. Refusal to provide informed consent or inability to complete the entire study protocol, among other factors; 3. Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥95 mmHg) or congestive heart failure classified as New York Heart Association (NYHA) Class III or IV; 4. Cognitively impaired or unable to comprehend the requirements of study participation.
Where this trial is running
Beijing, Beijing Municipality
- Peking University Third Hospital — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Fuzhen Yuan, Dr.
- Email: feng_yanggang@163.com
- Phone: +8618811728786
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.