Robot-assisted surgery for treating lymphedema in breast cancer patients

Pilot Study on Robotic Assisted Microsurgical Lymphatico-venular Anastomosis

NA · Maastricht University Medical Center · NCT06532955

This study is testing if robot-assisted surgery for lymphedema can help women with breast cancer feel better compared to traditional surgery done by hand.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexFemale
SponsorMaastricht University Medical Center (other)
Locations1 site (Maastricht, Limburg)
Trial IDNCT06532955 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of robot-assisted microsurgery for lymphaticovenous anastomosis (LVA) in patients suffering from breast cancer-related lymphedema. It compares the outcomes of robot-assisted LVA with manual LVA performed by the same expert surgeon. The study aims to assess various parameters including surgery duration, technical errors, surgeon satisfaction, and patient symptoms over time. A total of 60 female patients with early-stage lymphedema will be enrolled at Maastricht University Medical Center.

Who should consider this trial

Good fit: Ideal candidates are female patients who have been treated for early-stage breast cancer and are experiencing stage 1 or 2 lymphedema of the arm.

Not a fit: Patients with advanced stage lymphedema (stage 3) or those currently undergoing breast cancer treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve surgical outcomes and recovery for patients with breast cancer-related lymphedema.

How similar studies have performed: While robot-assisted microsurgery is a growing field, this specific application for lymphedema treatment is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female gender;
* Treated for primary early stage breast cancer;
* Early stage lymphedema of the arm (stage 1 or 2 on ISL classification);
* ELV \> 10%;
* Suffering from unilateral disease.

Exclusion Criteria:

* Male gender;
* Stage 3 lymphedema of the arm;
* Receiving current breast cancer treatment;
* Distant breast cancer metastases;
* Current substance abuse;
* History of marcaine or indocyanine green allergy;
* Non-viable lymphatic system as determined by near infrared imaging;
* Previous LVA (\<10 years) in the arm with lymphedema.

Where this trial is running

Maastricht, Limburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb, Surgical, Lymphedema, Secondary, Lymphedema of Limb, Lymphedema, Breast Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.