Robot-assisted hand training for children with cerebral palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of robot-assisted hand training using the Amadeo device in improving manual functions and promoting brain reorganization in children diagnosed with cerebral palsy (CP). Participants will undergo assessments of their manual motor and sensory functions before, immediately after, and two months following the training, utilizing behavioral tasks and advanced neuroimaging techniques like high-density electroencephalography (HD-EEG) and transcranial magnetic stimulation (TMS). The goal is to provide evidence on how this innovative rehabilitation approach can enhance recovery and potentially lead to predictive factors for functional improvements in CP patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* An evaluation by a pediatric neurologist, Physical Medicine and Rehabilitation (PMNR) physicians (physiatrists), neonatal developmental specialist, or neonatologist with a diagnosis of CP.
* Classified as high-functioning (I or II) at the Gross Motor Function Classification System (GMFCS)
* Participants in the control group should have no history of neurological disorder or brain injury

Exclusion Criteria:

* Psychoactive or myorelaxant medication during study procedures
* Genetic syndrome diagnosis
* History of trauma or brain operation
* Inability to sit still
* Metal implants
* Baclofen pump
* Inability or unwillingness of patient or parent/legally authorized representative to give written informed consent

Where it's running

• Cook Children's Medical Center
  Fort Worth, Texas, United States Recruiting

Study contacts

• Principal investigator: Christos Papadelis, PhD — Cook Children's Health Care System
• Study coordinator: Laurie J Bailey, PhD
• Email: laurie.bailey@cookchildrens.org
• Phone: 682-885-2488

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.