Right-heart ultrasound to predict success of removing the breathing tube in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, observational single-center study in adult ICU patients planned for weaning from mechanical ventilation. Bedside transthoracic echocardiography will be performed within two hours after patients meet clinical weaning criteria to measure TAPSE, tricuspid S', RV-FAC, right atrial area, and pulmonary valve acceleration time. Patients will be followed for 24 hours after extubation to record reintubation, need for noninvasive ventilation or high-flow oxygen, and other respiratory/physiologic data. Demographic and clinical variables (APACHE II, SOFA, ventilation settings, duration of ventilation) will be collected to relate cardiac measurements to weaning outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Receiving invasive mechanical ventilation in the ICU
* Planned extubation (weaning) according to standard clinical criteria
* Hemodynamically stable at the time of transthoracic echocardiography (TTE)
* Ability to undergo echocardiographic assessment within 2 hours prior to extubation
* Informed consent obtained from patient or legal representative

Exclusion Criteria:

* Known severe tricuspid valve disease or congenital heart disease
* Moderate to severe pericardial effusion or cardiac tamponade
* Inadequate acoustic window for transthoracic echocardiography
* Patients requiring urgent or unplanned extubation
* Use of extracorporeal life support (e.g., ECMO) at the time of assessment
* Known pulmonary embolism or acute cor pulmonale
* Pregnancy

Where it's running

• Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
  Istanbul, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Engin ihsan Turan, principal investigator
• Email: enginihsan@hotmail.com
• Phone: +905382431114

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07022704

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.