Reviewing medications for older patients with frailty
The Development and iMplementation Of a Multidisciplinary Medication Review and Deprescribing Intervention Among Frail Older People in primarY Care (MODIFY Study)
This study is trying to see how doctors and pharmacists can work together to improve medication reviews for older patients with frailty to make their prescriptions safer and more suitable.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | University of Southampton Academic / other |
| Locations | 1 site (Southampton) |
| Trial ID | NCT05705284 on ClinicalTrials.gov |
What this trial studies
This research investigates how practice-pharmacists, advanced nurse practitioners (ANPs), and general practitioners (GPs) can collaborate effectively to conduct regular medication reviews for older patients living with frailty. The study consists of four work packages, including a literature review to identify successful medication review strategies and interviews with healthcare professionals and patients to gather insights on the medication review process. The goal is to enhance the safety and appropriateness of medications prescribed to frail older adults, potentially reducing the risks associated with polypharmacy.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 65 and over who are frail and prescribed multiple medications.
Not a fit: Patients under 65 or those with severe cognitive impairment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to safer medication practices and improved health outcomes for frail older patients.
How similar studies have performed: Other studies have shown success in similar multidisciplinary approaches to medication review, indicating potential for positive outcomes in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Eligibility criteria for WP2 Patients: Inclusion criteria * Aged 65 and over * Frail, (as judged by their health care professional, if applicable) * Prescribed multiple medications (10+), as determined by their health care professional * Able to give informed consent Exclusion criteria * Aged under 65 * Severe cognitive impairment, as judged by their health care professional Informal carers/ relatives eligibility criteria Inclusion criteria * An informal carer/ relative of a frail patient (aged 65 and over) who is taking multiple medications, as identified by a health care professional * An informal carer/ relative of a patient (aged 65 and over) living with severe dementia who is taking multiple medications, as identified by a health care professional * Able to consent Health care professional eligibility criteria • A health care professional based in GP surgeries in Wessex (eg. GPs, practice-pharmacists, advanced nurse prescriber (ANPs) who works with older people living with frailty, who are prescribed multiple medications.
Where this trial is running
Southampton
- Clinical Research Network in Primary Care — Southampton, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Kinda Ibrahim, PhD — University of Southampton
- Study coordinator: Eloise Radcliffe, PhD
- Email: e.radcliffe@soton.ac.uk
- Phone: (023) 8120 4656
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.