Restoring ovarian function using autografted ovarian tissue
Development of Ovarian Tissue Autograft in Order to Restore Ovarian Function
NA · Centre Hospitalier Universitaire de Besancon · NCT02846064
This study is testing whether using frozen ovarian tissue can help women with ovarian function issues regain their fertility and have healthy pregnancies.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 43 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier Universitaire de Besancon (other) |
| Locations | 1 site (Besançon) |
| Trial ID | NCT02846064 on ClinicalTrials.gov |
What this trial studies
This clinical trial focuses on the use of autografted cryopreserved ovarian tissue to restore ovarian function in women who have experienced ovarian function insufficiency. It aims to collect data on the effectiveness of this approach in terms of restoring ovarian function and achieving live births. The study will also monitor patients after the cryopreservation and autograft procedures, ensuring safety by detecting any residual disease in cases of previous malignancies. The trial is conducted at multiple university hospitals in France.
Who should consider this trial
Good fit: Ideal candidates include women aged 18 to 43 who have undergone ovarian tissue cryopreservation and have experienced premature ovarian failure.
Not a fit: Patients who are under legal guardianship or conservatorship will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve fertility options for women with ovarian function insufficiency.
How similar studies have performed: Previous studies have shown success with ovarian tissue autografting, including a notable live birth in France, indicating potential for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent Ovarian tissue cryopreservation * Premature ovarian failure * Patients cured of their primary disease * Women between 18 and 43 years of age * Patients who have already benefited from ovarian tissue autograft Exclusion Criteria: * Patients under trusteeship * Patients placed in receivers * Patients under the protection of a conservator
Where this trial is running
Besançon
- CHRU Besancon — Besançon, France (RECRUITING)
Study contacts
- Study coordinator: Clotilde AMIOT, MD PhD
- Email: clotilde.amiot@univ-fcomte.fr
- Phone: +33381218681
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ovarian Function Insufficiency