Resistance training for individuals with mild cognitive impairment and dementia
Effects of Different Resistance Training Volumes on Cognitive Function, Oxidative Stress, Immunological Response, Lipid Profile, Glycemic Status, Liver Function, Muscle Function, Hemodynamic Response, and Physical Performance in Individuals With Mild Cognitive Impairment
NA · University of Beira Interior · NCT06185010
This study tests whether different amounts of resistance training can improve health and cognitive function in people with mild cognitive impairment and dementia.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of Beira Interior (other) |
| Locations | 1 site (Covilha) |
| Trial ID | NCT06185010 on ClinicalTrials.gov |
What this trial studies
This project investigates the effects of different volumes of resistance training on various health parameters in individuals with mild cognitive impairment. Initially, participants will undergo two resistance training sessions to assess acute effects on hemodynamic and physical performance. Following this, an 8-week program will be implemented, comparing one-set and three-set training regimens, with evaluations on cognitive function, oxidative stress, and other health metrics before and after the intervention. A control group will also be included for comparison.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with mild cognitive impairment who can participate in physical exercise.
Not a fit: Patients with severe dementia or significant comorbidities that hinder participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance cognitive function and overall health in patients with mild cognitive impairment.
How similar studies have performed: Other studies have shown positive outcomes with resistance training in similar populations, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Clinical diagnosis of mild cognitive impairment * SPPB score ≥ 3 points * Willingness to participate in the interventions and collaborate with the research team * Must be able to provide informed consent (oral or written) Exclusion criteria: * Severe dementia * Severe comorbidity that negatively influences participation in the intervention * Color blindness * Fractures in the last three months
Where this trial is running
Covilha
- University of Beira Interior — Covilha, Portugal (RECRUITING)
Study contacts
- Principal investigator: Mário C Marques, PhD — University of Beira Interior
- Study coordinator: Nuno Fonseca, Master's
- Email: nuno1977fonseca@gmail.com
- Phone: 918241354
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Mild Cognitive Impairment, Mild Dementia