Clinical trial Recruiting at 1 site Interventional Ages 60 to 79 Women only

Resistance exercise training for older women with obesity

Official title: Effects of a Resistance Exercise Training Program on Skeletal Muscle Quality, Immune Response and Physical Performance in Normal Weight Versus Obesity Older Women

Run by Universidad de La Frontera · NCT06367296 · Data updated 2026-11-12

This study is testing if a 12-week strength training program can help older women with obesity improve their muscle strength and overall health compared to those of normal weight.

Quick facts

Study typeInterventional
Ages60 Years to 79 Years
SexWomen only
Enrollment32 (estimated)
SponsorUniversidad de La Frontera
Academic / other
Locations2 sites (Temuco, Araucania and 1 other locations)
StatusRecruiting
StartedJuly 1, 2024
Main results expectedJanuary 28, 2025
Study endsJune 1, 2025
Registry record updatedJanuary 27, 2025
Trial IDNCT06367296 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are older women aged 60 to 79 years, both with obesity and normal weight, who live in the community and can follow verbal instructions.

Probably not a fit

Patients with neuromuscular or mobility disorders that prevent safe participation in resistance training will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of a 12-week resistance exercise training program on muscle quality, immune response, and physical performance in older women aged 60 to 79 years. It compares the outcomes between those with obesity and those of normal weight, focusing on the impact of strength training on muscle quality and inflammation. The study aims to determine if women with obesity experience greater improvements due to their baseline conditions. Participants will engage in prolonged resistance exercise training to assess these effects.

Why it matters

Potential benefit: If successful, this program could significantly improve muscle quality and overall health in older women, particularly those with obesity.

How similar studies have gone: Previous studies have shown that resistance training can improve muscle mass and quality in older populations, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Older women between 60 and 79 years old who live in the community, that is, they do not live in nursing homes or similar.
* Older people with normal weight (BMI=18.5 to 24.9 kg/m2 and % fat \<25.9) and those with obesity (BMI= 30 to 39.9 Kg/m2 and % fat \> 32).
* Cognitive ability to follow verbal orders.

Exclusion Criteria:

* Neuromuscular or mobility disorders that do not allow resistance training to be carried out safely (debilitating arthritis, spasticity/rigidity, neurological disorders and paralysis).
* Use of nutritional supplementation that can regulate skeletal muscle (leucine, glutamine, casein, whey-protein, fatty acids and creatine).
* Untreated and/or uncontrolled chronic diseases.
* Have carried out a training program with resistance exercises in the last 6 months.

Where it's running

  • Gabriel Marzuca
    Temuco, Araucania, Chile
    Recruiting
  • Universidad de La Frontera
    Temuco, IX Región de La Araucanía, Chile
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.