Resistance exercise training for older women with obesity
Effects of a Resistance Exercise Training Program on Skeletal Muscle Quality, Immune Response and Physical Performance in Normal Weight Versus Obesity Older Women
This study is testing if a 12-week strength training program can help older women with obesity improve their muscle strength and overall health compared to those of normal weight.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 60 Years to 79 Years |
| Sex | Female |
| Sponsor | Universidad de La Frontera Academic / other |
| Locations | 2 sites (Temuco, Araucania and 1 other locations) |
| Trial ID | NCT06367296 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of a 12-week resistance exercise training program on muscle quality, immune response, and physical performance in older women aged 60 to 79 years. It compares the outcomes between those with obesity and those of normal weight, focusing on the impact of strength training on muscle quality and inflammation. The study aims to determine if women with obesity experience greater improvements due to their baseline conditions. Participants will engage in prolonged resistance exercise training to assess these effects.
Who should consider this trial
Good fit: Ideal candidates are older women aged 60 to 79 years, both with obesity and normal weight, who live in the community and can follow verbal instructions.
Not a fit: Patients with neuromuscular or mobility disorders that prevent safe participation in resistance training will not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly improve muscle quality and overall health in older women, particularly those with obesity.
How similar studies have performed: Previous studies have shown that resistance training can improve muscle mass and quality in older populations, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Older women between 60 and 79 years old who live in the community, that is, they do not live in nursing homes or similar. * Older people with normal weight (BMI=18.5 to 24.9 kg/m2 and % fat \<25.9) and those with obesity (BMI= 30 to 39.9 Kg/m2 and % fat \> 32). * Cognitive ability to follow verbal orders. Exclusion Criteria: * Neuromuscular or mobility disorders that do not allow resistance training to be carried out safely (debilitating arthritis, spasticity/rigidity, neurological disorders and paralysis). * Use of nutritional supplementation that can regulate skeletal muscle (leucine, glutamine, casein, whey-protein, fatty acids and creatine). * Untreated and/or uncontrolled chronic diseases. * Have carried out a training program with resistance exercises in the last 6 months.
Where this trial is running
Temuco, Araucania and 1 other locations
- Gabriel Marzuca — Temuco, Araucania, Chile (Recruiting)
- Universidad de La Frontera — Temuco, IX Región de La Araucanía, Chile (Not_yet_recruiting)
Study contacts
- Study coordinator: Nicolás Vidal-Seguel, MSc
- Email: nicolasenrique.vidal@ufrontera.cl
- Phone: 998595445
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.