Research on the genetics of Parkinson's disease in families
The Parkinson's Genetic Research Study (PaGeR)
This study is trying to find out if certain genes in families with multiple members affected by Parkinson's disease can help us understand why some people get the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Washington Academic / other |
| Locations | 5 sites (Atlanta, Georgia and 4 other locations) |
| Trial ID | NCT01558479 on ClinicalTrials.gov |
What this trial studies
The Parkinson's Genetic Research Study (PaGeR) aims to identify genes that may increase the risk of developing Parkinson's disease by focusing on families with multiple affected members. Participants will complete a questionnaire, undergo interviews, neurological exams, memory tests, and provide blood samples. This observational study is a collaborative effort among neurologists and researchers across the United States, coordinated by the University of Washington and the VA Puget Sound Health Care System. The study is sponsored by the National Institutes of Health and aims to uncover genetic factors contributing to Parkinson's disease.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 who are part of families with two or more living individuals diagnosed with Parkinson's disease.
Not a fit: Patients under 18 years of age will not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential prevention strategies for Parkinson's disease.
How similar studies have performed: Previous studies focusing on genetic factors in familial Parkinson's disease have shown promise, suggesting that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Over 18 years of age * Member of a family in which there are two or more living individuals who have been diagnosed with Parkinson's disease Exclusion Criteria: * Under 18 years of age
Where this trial is running
Atlanta, Georgia and 4 other locations
- Emory University/ Wesley Woods Health Center — Atlanta, Georgia, United States (Recruiting)
- University of Cincinnati — Cincinnati, Ohio, United States (Recruiting)
- Portland VA Medical Center — Portland, Oregon, United States (Recruiting)
- VA Puget Sound Health Care System — Seattle, Washington, United States (Recruiting)
- University of Washington — Seattle, Washington, United States (Recruiting)
Study contacts
- Principal investigator: Cyrus Zabetian, MD, MS — University of Washington, VA Puget Sound Health Care System
- Study coordinator: Jennifer Pate
- Phone: 1-855-646-4221
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.