Research on the causes of fatigue in cancer and chronic fatigue syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the underlying causes of Cancer Related Fatigue (CRF) and Chronic Fatigue Syndrome (CFS/ME) by analyzing lipidomics, metabolomics, microbiomes, and exomes in patients with tumor diseases. Participants will be compared to age- and gender-matched control groups to identify differences in these biological markers. Additionally, the study will explore the potential benefits of probiotics in alleviating fatigue symptoms through a double-blinded, placebo-controlled approach. The research aims to provide insights into the pathophysiology of these conditions and evaluate the effectiveness of probiotics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* histologically, cytologically or radiologically confirmed tumor disease
* indication for chemotherapy
* Written consent to participation

Exclusion Criteria:

* chronic-inflammatory bowel disease
* pregnancy

Where it's running

• Saarland University Medical Center
  Homburg, Saarland, Germany Recruiting

Study contacts

• Principal investigator: Michael Jelden, MD — University Hospital, Saarland
• Study coordinator: Michael Jelden, MD
• Email: michael.jelden@uks.eu
• Phone: +4968411630000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.