Research on placental function in healthy and complicated pregnancies
Study of Placental Function in Healthy and Pathological Pregnancies
University of Colorado, Denver · NCT02321007
This study is collecting samples from healthy and complicated pregnancies to see how changes in the placenta might affect the health of both the mother and baby.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1250 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | University of Colorado, Denver (other) |
| Locations | 1 site (Aurora, Colorado) |
| Trial ID | NCT02321007 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a repository of tissue and data by collecting samples from human placentas, umbilical cord blood, and maternal blood at delivery. The collected specimens will be utilized in various cellular, molecular, and functional studies to investigate changes in placental structure and function. Understanding these changes is crucial as they can lead to serious pregnancy complications and influence the long-term health of the fetus, potentially programming them for future metabolic and cardiovascular diseases.
Who should consider this trial
Good fit: Ideal candidates include healthy women delivering at term and those experiencing pregnancy complications such as pre-term birth, intrauterine growth restriction, diabetes, or obesity.
Not a fit: Patients under stress or experiencing labor pain, as well as those with other pregnancy complications, may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of placental health and its impact on pregnancy outcomes, leading to improved management of pregnancy complications.
How similar studies have performed: Other studies have shown success in understanding placental function and its implications for pregnancy health, making this approach both relevant and valuable.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy women delivering at term * Women with pregnancy complications such as: * pre-term birth, * intrauterine growth restriction, * diabetes, and * obesity. Exclusion Criteria: * Women: * under stress, * experiencing pain of labor. * Pregnancies complicated by other pathologies.
Where this trial is running
Aurora, Colorado
- University of Colorado Hospital — Aurora, Colorado, United States (RECRUITING)
Study contacts
- Principal investigator: Thomas Jansson, MD, PhD — University of Colorado, Denver
- Study coordinator: Anita Kramer
- Email: anita.kramer@ucdenver.edu
- Phone: 303-724-1653
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pregnancy