Research on families with exceptional longevity in the Netherlands

Longevity Families of the Netherlands

Observational Leiden University Medical Center · NCT06374069

This study looks at families in the Netherlands with members who live a long time to see what genes and life habits help them age healthily.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages75 Years and up
SexAll
SponsorLeiden University Medical Center Academic / other
Locations1 site (Leiden, South Holland)
Trial IDNCT06374069 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the genetic and environmental factors that contribute to healthy aging and longevity among families in the Netherlands. It focuses on individuals aged 75 and older, particularly those with a family history of exceptional longevity. The research will identify gene variants linked to healthy aging and examine the social, environmental, and behavioral influences on longevity and morbidity. By understanding these factors, the study seeks to uncover mechanisms that promote a longer, healthier life.

Who should consider this trial

Good fit: Ideal candidates for this study are Dutch Caucasian individuals aged 75 and older, particularly those with a family history of longevity.

Not a fit: Patients who are younger than 75 or do not have a familial background of longevity may not benefit from this study.

Why it matters

Potential benefit: If successful, this research could lead to insights that enhance healthy aging and longevity for future generations.

How similar studies have performed: Other studies have shown promise in understanding the genetic and environmental factors of longevity, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Siblings of Dutch Caucasian descent age 75+ enriched for familial longevity
* Individuals of Dutch Caucasian descent age 75+ who are not enriched for familial longevity

Exclusion Criteria:

\-

Where this trial is running

Leiden, South Holland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LongevityFamilial LongevityExtreme LongevityAging
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.