Research on Alzheimer's disease in Arizona
Arizona Alzheimer's Disease Research Center (ADRC)
This study is trying to learn more about Alzheimer's disease by looking at brain health in people with different levels of memory issues and collecting samples to help find new treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 550 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Banner Health Academic / other |
| Locations | 5 sites (Phoenix, Arizona and 4 other locations) |
| Trial ID | NCT05405075 on ClinicalTrials.gov |
What this trial studies
The Arizona Alzheimer's Disease Research Center (ADRC) focuses on understanding Alzheimer's disease through a collaborative approach that leverages Arizona's strengths in various scientific fields. It involves cognitive assessments and the collection of biological samples from participants, including those who are cognitively normal, have mild cognitive impairment, or dementia. The center aims to discover and evaluate new treatments while also studying normal cognitive aging. This observational study will contribute to a better understanding of Alzheimer's disease and its progression.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 40 and older who are cognitively normal or have mild cognitive impairment or dementia.
Not a fit: Patients with cognitive impairment due to conditions unrelated to Alzheimer's disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease.
How similar studies have performed: Other studies focusing on Alzheimer's disease have shown success in understanding its mechanisms and developing potential treatments, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cognitively normal persons, individuals with mild cognitive impairment or dementia who are at least 40 years of age. * Willing to undergo health and cognitive assessments, and collection and banking of blood with venipuncture for genetic research, biomarker research, and DNA banking. Exclusion Criteria: * 1\. Participants whose diagnosis is unclear and confounded by multiple possible factors are excluded. Participants with diagnoses of non-AD dementias are not excluded. 2\. Participants whose primary diagnosis is cognitive impairment due to a penetrating or single severe closed head injury, multiple sclerosis, brain tumor, metabolic or toxic encephalopathy, post-infectious (e.g., viral encephalitis, bacterial meningitis), paraneoplastic, primary psychiatric illness, or otherwise not deemed relevant to the intent of the Alzheimer Disease Center program are excluded. 3\. Procedure specific exclusion criteria also apply but this does not impact the participants ability to be included in the study.
Where this trial is running
Phoenix, Arizona and 4 other locations
- Banner Alzheimer's Institute — Phoenix, Arizona, United States (Recruiting)
- Barrow Neurological Institute — Phoenix, Arizona, United States (Recruiting)
- Mayo Clinic — Scottsdale, Arizona, United States (Recruiting)
- Banner Sun Health Research Institute — Sun City, Arizona, United States (Recruiting)
- Banner Alzheimer's Institute - Tucson — Tucson, Arizona, United States (Recruiting)
Study contacts
- Study coordinator: Trisha Walsh
- Email: ADRC@bannerhealth.com
- Phone: 602.839.6029
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.