Repairing longitudinal meniscus tears using fibrin clots
Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears - A Prospectively Randomized Controlled Trial
This study is testing if using a special treatment called fibrin clots during surgery can help people with meniscus tears heal better than the usual repair methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Ankara City Hospital Bilkent Academic / other |
| Locations | 2 sites (Ankara and 1 other locations) |
| Trial ID | NCT06541756 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of fibrin clot-augmented meniscal repair compared to standard meniscal repair for patients with longitudinal meniscus tears. Participants aged 18 to 50 will be randomly assigned to receive either the fibrin clot-enhanced repair or conventional repair techniques. The fibrin clot will be prepared from bone marrow aspirate and used to reinforce the meniscal repair. Patients will be followed for at least one year post-surgery to assess healing rates through MRI evaluations.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 to 50 with a painful longitudinal meniscus tear who have not had prior surgery on the same knee.
Not a fit: Patients with additional ligament damage, previous knee surgeries, or active infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve healing rates and long-term outcomes for patients with meniscus tears.
How similar studies have performed: While the use of fibrin clots in surgical repairs is a novel approach, similar studies have shown promising results in enhancing healing in other types of tissue repairs.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presenting with a painful meniscus (lateral or medial) longitudinal tear * Being between the ages of 18 and 50 * Not having undergone surgery on the same knee before * Having an MRI taken at the end of the 1st year post-surgery Exclusion Criteria: * Having additional collateral ligamentous damage along with the meniscus tear (such as MCL or LCL) * Incomplete clinical scores at the end of the study * A history of previous surgery on the same knee * Having an active infection * Not having a control MRI at the end of the 1st year
Where this trial is running
Ankara and 1 other locations
- Ankara Bilkent City Hospital — Ankara, Turkey (Türkiye) (Recruiting)
- Ankara Etlik City Hospital — Ankara, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Enejd Veizi, MD — Ankara City Hospital Bilkent
- Study coordinator: Enejd Veizi, MD
- Email: dr.nad89@hotmail.com
- Phone: +905439799959
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.