Remote intervention for weight regain after bariatric surgery

Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain

NA · Temple University · NCT06292936

This study is testing if a new remote program can help people who have gained weight after bariatric surgery lose that weight and improve their health.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorTemple University (other)
Locations2 sites (Chicago, Illinois and 1 other locations)
Trial IDNCT06292936 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of a remotely-delivered acceptance-based behavioral intervention (ABTi) for bariatric surgery patients who have experienced significant weight regain postoperatively. Participants will be randomly assigned to either the ABTi group or a control group that receives standard dietary and behavioral guidance. The study will assess changes in body weight and related behaviors over a 12-month period, focusing on individuals who have regained more than 5% of their lowest postoperative weight. The goal is to determine if ABTi can effectively reverse weight regain and improve weight-related health outcomes.

Who should consider this trial

Good fit: Ideal candidates are men and women aged 18-70 who have regained at least 5% of their weight after undergoing gastric bypass or sleeve gastrectomy within the last 6 to 48 months.

Not a fit: Patients currently using weight loss medications, those with recent psychiatric issues, or those who have lost significant weight recently may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could help patients regain control over their weight and improve their overall health after bariatric surgery.

How similar studies have performed: Other studies have shown promise with behavioral interventions for weight management, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men and women
* Ages 18-70 years old
* Weight regain of at least 5% from lowest postoperative weight
* Body mass index (BMI) 25 or above
* Underwent gastric bypass or sleeve gastrectomy within 6 to 48 months prior to enrollment
* Ability to give consent
* Ability to speak, write, and understand English

Exclusion Criteria:

* Long-term treatment with oral steroids
* Current use of weight loss medication (OTC or prescription)
* Current pregnancy, plan to become pregnant within 12 months, lactation within the past 6 months
* Psychiatric hospitalization in the past 6 months
* Documented or self-reported psychiatric diagnosis that would interfere with adherence to the study protocol or acute suicidality
* Self-report of alcohol or substance abuse within the past 12 months
* Current, self-reported use of tobacco products
* Weight loss \> 10 lbs in the past 3 month
* History of more than one bariatric procedure
* Inability to walk at least one city block without assistance

Where this trial is running

Chicago, Illinois and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Obesity, Bariatric Surgery Candidate, Acceptance-Based Behavioral Therapy, Postoperative Outcomes, Weight Regain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.