Remote high-intensity resistance exercise with home sleep monitoring for Parkinson's disease
Adapting High-Intensity Exercise and Sleep Monitoring Technology for Home Use in Parkinson's Disease
This project will test whether a remotely delivered high-intensity resistance exercise program plus a home sleep-monitoring device can be used safely and easily by people with Parkinson's disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 16 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Aurora, Colorado) |
| Trial ID | NCT07498296 on ClinicalTrials.gov |
What this trial studies
Investigators will adapt a laboratory-based high-intensity resistance exercise (HIRE) protocol for remote, home-based delivery using the IDEAS framework to guide design for safety, accessibility, and fidelity. Participants who live in Colorado and have internet and a video-capable device will follow the modified exercise program remotely while using a wearable or home sleep-monitoring device. The study will collect usability data on the sleep-monitoring device, adherence and safety metrics for the remote HIRE protocol, and compare these outcomes to prior in-lab findings. Key exclusions include uncontrolled cardiac or pulmonary disease, significant musculoskeletal injury, high fall risk, or regular participation in community PD exercise programs (>3 days/week).
Who should consider this trial
Good fit: Ideal candidates are people with Parkinson's who live in Colorado, require less than minimal home assistance, have internet and a video-capable device, score ≥18 on the virtual MoCA, and have no uncontrolled cardiac/pulmonary disease or major musculoskeletal limitations.
Not a fit: Patients with uncontrolled heart or lung disease, significant musculoskeletal injuries, high fall risk, frequent community exercise participation (>3 days/week), or without reliable internet/video access are unlikely to benefit from the remote program.
Why it matters
Potential benefit: If successful, this approach could let more people with Parkinson's do effective high-intensity resistance training at home and potentially improve sleep and symptom management while reducing barriers like transportation.
How similar studies have performed: A prior laboratory-based randomized trial showed that HIRE improved sleep efficiency in people with Parkinson's, but remote delivery and home sleep-monitoring represent novel adaptations that have limited prior testing.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Currently residing in Colorado, USA * PD diagnosis per Movement Disorders Society Diagnostic Criteria * Requiring less than minimal assistance at home * Having internet access * Having a video-capable device Exclusion Criteria: * Uncontrolled cardiovascular disease or pulmonary disease * Musculoskeletal injuries * Participation in Parkinson's Disease community exercise programs more than 3 days a week * Contraindication to physical activity as determined by the Physical Activity Readiness Questionnaire (PAR-Q) * Fall risk defined by requiring \>20 seconds to complete the 5 times sit to stand test14 or high frequency of falls within the past year (≥ one fall per month) * Virtual Montreal Cognitive Assessment (MoCA) score ≥ 18 (performed at the eligibility visit)
Where this trial is running
Aurora, Colorado
- University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States (Recruiting)
Study contacts
- Study coordinator: Lina Kleinschmidt, DPT
- Email: lina.kleinschmidt@cuanschutz.edu
- Phone: 18058861854
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.