Relationship between central sensitization and clinical features in plantar fasciitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines how neurophysiological measures (pressure pain threshold and central sensitization), pain intensity, psychological factors (kinesiophobia, catastrophizing, anxiety, and depression), ultrasound findings (plantar fascia thickness), and functional outcomes relate in adults with plantar fasciitis. Researchers will collect data on pain thresholds, pain perception, psychological questionnaires, ultrasound measurements, and functional indices to explore possible associations. The study does not assign treatments but seeks to identify factors that contribute to pain and function in plantar fasciitis. Findings may help clarify the role of central sensitization and psychological factors in this condition. Participant data will be gathered from adults with unilateral heel pain lasting at least 3 months at a single hospital site.

Why it matters

Who can join: the full rules

Plantar Fasciitis Group

1. Inclusion criteria

   * Be between the ages of 18-65
   * Have unilateral heel pain that has been ongoing for at least 3 months, particularly worsening with the first few steps in the morning and increasing with weight-bearing activities throughout the day
   * Have tenderness on palpation of the medial calcaneal tubercle
   * Have read and signed the volunteer consent form (VCF)
2. Exclusion criteria

   * Being under 18 years old or over 65 years old
   * Having a history of physical therapy, injection, radiation, or surgery targeting the plantar fascia within the last 6 months
   * Calcaneus fracture, tumor, or cyst related to the plantar fascia
   * Foot deformity (club foot, pes cavus, calcaneovalgus, etc.)
   * Lumbosacral radiculopathy, tarsal tunnel syndrome, peripheral neuropathy
   * Rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, gout
   * Foot and ankle osteoarthritis
   * Presence of osteomyelitis or skin infection in the foot
   * Systemic diseases such as kidney and liver failure, diabetes, peripheral arterial vascular disease

Healthy Control

1. Inclusion criteria

   * Being completely healthy
   * Being between the ages of 18 - 65
   * Having read and signed the volunteer consent form (BGOF)
2. Exclusion criteria

   * Being under 18 or over 65 years old
   * Having any acute or chronic illness
   * Being illiterate and not giving consent to participate in the study

Where it's running

• Sultan Abdulhamid Han Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Feyza Nur Yücel — Saglik Bilimleri Universitesi
• Study coordinator: Feyza Nur Yücel, Assoc. Prof.
• Email: dr.fny28@gmail.com
• Phone: 2165422000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Extracorporeal Shock Wave Therapy With or Without Kinesio Taping for Plantar Fasciitis

  This study tests whether adding kinesio taping to shock wave therapy helps reduce pain and improve foot function in people with plantar fasciitis.

  Recruiting Ankara City Hospital Bilkent · Ankara, Çankaya · NCT07864948

• Transverse Friction Massage vs Instrument-Assisted Soft-Tissue Mobilization for Plantar Fasciitis

  This study tests whether transverse friction massage or instrument-assisted soft-tissue mobilization helps people with plantar fasciitis feel better.

  Recruiting Foundation University Islamabad · Islamabad, Punjab Province · NCT07856147

• Ice packs vs cold baths with standard exercise for heel pain from plantar fasciitis

  This trial tests whether ice packs or cold baths, when added to a standard exercise plan, better reduce pain for adults with plantar fasciitis.

  Recruiting Ibadat International University, Islamabad · Peshawar, Khyber Pakhtunkhwa · NCT07694999

• Do Myofascial Release or Instrument-Assisted Soft Tissue Mobilization Help Pregnant Women with Plantar Fasciitis

  This study tests whether two manual therapy techniques, MFR and IASTM, can reduce heel pain and improve foot function in pregnant women with plantar fasciitis.

  Recruiting University of Lahore · Lahore, Punjab Province · NCT07676058

• Barefoot Walking vs Standardised Conservative Care for Plantar Fasciopathy

  This trial tests whether a barefoot walking program can reduce heel pain and improve foot function in adults with plantar fasciopathy compared with a standard stretching and strengthening program.

  Recruiting South East Technological University · Carlow, Carlow County · NCT07600229

• Lateral plantar artery embolization for chronic heel pain

  This will test whether injecting a temporary blocking agent (Lipiodol) into the lateral plantar artery can reduce chronic heel pain in adults 25–80 who have not improved after at least three months of conservative care.

  Recruiting Phase 1 Joint & Vascular Institute · Libertyville, Illinois · NCT07395128

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.