Reinforced resin versus monolithic zirconia for screw-retained implant prostheses: effects on bone height and biting force

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase 2 interventional trial compares digitally fabricated screw-retained mandibular implant supra-structures made from biomimetic reinforced resin versus monolithic zirconia. Eligible adults (30–60) with partially edentulous mandibular Class II arches and a fully dentate opposing maxilla will receive one of the two suprastructures and be followed over scheduled visits. Primary outcomes are radiographic marginal bone height changes and intra-oral biting force measurements, with secondary outcomes including prosthetic complications, soft tissue response, color stability, and bacterial adhesion. The trial aims to determine whether a more biomimetic resin material can reduce mechanical complications and improve clinical durability compared with rigid zirconia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Mandibular Class II, partially edentulous patients that enables measuring the marginal bone height changes and values of biting forces intra-orally.
* Fully dentulous edentulous opposing Maxillary arch.
* Patients with normal class I jaw relationship.
* Patients that require fixed restorations for functional and esthetic reasons
* Age range (30-60 years).
* Cooperative patients those are willing to attend all follow-up periods.
* Patients with healthy attached mucosa of appropriate thickness free from any inflammation.
* Patients with healthy bone of appropriate thickness, width and height free from any inflammation.
* Patients without any medical conditions that contraindicates implant placement.

Exclusion Criteria:

* Patients with Parkinson's disease
* Patients with xerostomia.
* Patients with a history of allergy to resins and/ or zirconia.
* Patients with a medical systematic condition that contraindicate implant placement.
* Patients smoking more than 10 cigarettes per day.
* Patients with pathological changes of residual ridges as recurrent or persistent ulcers, osteomyelitis and infections.
* Patients with large irregular bony exostosis.
* Patients with medical or psychological conditions as physical disability or mental retardation that hinder cooperation in the follow up visits and answering the questionnaires.

Where it's running

• Faculty of Dentistry, Cairo University
  Cairo, Cairo Governorate, Egypt Recruiting
• Faculty of Dentistry, Cairo University
  Cairo, Cairo Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mahmoud Saleh Fayed, Assistant lecturer
• Email: mahmoud.fayed@dentistry.cu.edu.eg
• Phone: 00201141565676

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.