Rehabilitation training using music for COPD and chronic respiratory failure patients
Official title: Can Rehabilitation Training With Music-support Increase Exercise Tolerance in Individuals With COPD and CRF Compared to Rehabilitation Training Alone? A Randomized Control Trial.
Run by Istituti Clinici Scientifici Maugeri SpA · NCT05720780 · Data updated 2026-11-12
This study tests if adding music to rehabilitation training can help people with COPD and chronic respiratory failure exercise better and feel less short of breath.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 85 Years |
| Sex | All |
| Enrollment | 156 (estimated) |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 6 sites (Telese Terme, Benevento and 5 other locations) |
| Status | Recruiting |
| Started | January 26, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | April 30, 2027 |
| Registry record updated | February 23, 2026 |
| Trial ID | NCT05720780 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with COPD and chronic respiratory failure who are clinically stable and have been on long-term oxygen therapy.
✕Probably not a fit
Patients with cognitive impairments, active infections, or other significant comorbidities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of incorporating music as a distracting auditory stimulus during rehabilitation training for patients with Chronic Obstructive Pulmonary Disease (COPD) and chronic respiratory failure (CRF). The study aims to compare exercise capacity, endurance, and perception of dyspnea between a group receiving music-supported training and a control group undergoing standard rehabilitation without music. By utilizing music therapy techniques, the trial seeks to enhance the psychological and physiological outcomes of rehabilitation. Participants will be monitored for improvements in exercise tolerance and overall quality of life.
Why it matters
Potential benefit: If successful, this approach could significantly improve exercise capacity and quality of life for patients with COPD and CRF.
How similar studies have gone: Previous studies have shown promising results with music therapy in rehabilitation contexts, suggesting potential for success in this novel application for COPD patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of COPD (Forced expiratory volume in 1 second / post-bronchodilator forced vital capacity \< 0.7) without functional reversibility * Chronic respiratory failure with stable hypoxia (PaO2 \< 60 mmHg in room air) * Long Term Oxygen Therapy (LTOT) for at least 3 months * Clinical stability: pH range 7.38-7.42, with no recent exacerbations in the last 7 days and no changes in drug therapy in the previous 7 days Exclusion Criteria: * Non-invasive ventilation at home * Cognitive impairment (Mini-Mental State Examination Score \< 22) * Asthma or evidence of bronchodilator response * Pulmonary fibrosis * Obstructive sleep apnea syndrome * Lung cancer * Active microbial infections * Neuromuscular, orthopedic, and/or medical conditions that preclude testing * Pulmonary rehabilitation program in the previous 6 months
Where it's running
-
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane
Lumezzane, Brescia, Italy Recruiting -
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano
Montescano, Pavia, Italy Recruiting -
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate
Tradate, Varese, Italy Recruiting -
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Pavia
Pavia, Italy Recruiting -
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Telese
Telese Terme, Benevento, Italy Not yet recruiting -
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Bari
Bari, Italy Not yet recruiting
Study contacts
- Study coordinator: Michele Vitacca, MD
- Email: michele.vitacca@icsmaugeri.it
- Phone: 0039+030+8253
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.