Rehabilitation program for spastic ataxias
Official title: IMPACT, a Supervised Rehabilitation Program for Spastic Ataxias: A Rater-blinded, Randomized Controlled Trial
Run by Laval University · NCT06261424 · Data updated 2026-11-12
This study is testing a 12-week rehabilitation program to see if it can help people with specific types of spastic ataxia feel better compared to regular care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | Laval University Academic / other |
| Locations | 5 sites (Baie-Saint-Paul, Quebec and 4 other locations) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | April 2026 |
| Study ends | March 2027 |
| Registry record updated | February 18, 2026 |
| Trial ID | NCT06261424 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with a confirmed genetic diagnosis of ARSACS or SPG7 who can maintain a standing position and provide informed consent.
✕Probably not a fit
Patients with other conditions causing physical limitations or those uncomfortable in a swimming pool may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effects of a 12-week supervised rehabilitation program on individuals with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay and Spastic Paraplegia 7. The program aims to improve disease severity compared to usual care, identify factors influencing its implementation in clinical settings, and explore the cost-benefits of the rehabilitation approach. Participants will engage in targeted exercises designed to address their specific symptoms, with the program having been previously pilot-tested for effectiveness.
Why it matters
Potential benefit: If successful, this program could significantly improve mobility and quality of life for patients suffering from spastic ataxias.
How similar studies have gone: While there is limited research specifically targeting spastic ataxias, similar rehabilitation programs for other neurological conditions have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * have a confirmed genetic diagnosis of ARSACS or SPG7 * be able to maintain standing position and to transfert * be authorized by their treating neurologist * speak French or English * be able to give informed consent. Exclusion Criteria: * have active participation in a rehabilitation program (self-reported information) * have another condition causing physical limitations * be uncomfortable in a swimming pool * be pregnant.
Where it's running
-
CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau
Montreal, Quebec, Canada Recruiting -
CIUSSS de la Capitale-Nationale, installation IRDPQ
Québec, Quebec, Canada Recruiting -
Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière
Saguenay, Quebec, Canada Recruiting -
CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul
Baie-Saint-Paul, Quebec, Canada Not yet recruiting -
CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie
La Malbaie, Quebec, Canada Not yet recruiting
Study contacts
- Study coordinator: Elise Duchesne, Ph D.
- Email: educhesn@uqac.ca
- Phone: 418-590-3552
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.