Rehabilitation program for patients with Long Haul COVID
Long Haul COVID Rehabilitation & Research Program
This study is testing a 10-week rehabilitation program to see if it helps people with Long Haul COVID feel better physically and mentally, comparing results from those who participate online versus in person.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Torrance, California) |
| Trial ID | NCT05398692 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effects of a 10-week rehabilitation program on patients suffering from Long Haul COVID. It will assess physiological, immunological, and mental health outcomes, comparing results between virtual and on-site pulmonary rehabilitation. The study hypothesizes that participants will experience reduced symptoms, improved physical status, lower inflammatory markers, and enhanced psychological well-being after completing the program.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have documented Long Haul COVID symptoms for at least 12 weeks.
Not a fit: Patients unable to perform necessary pulmonary function tests or those currently enrolled in another pulmonary rehabilitation program may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly improve the quality of life for patients suffering from Long Haul COVID.
How similar studies have performed: Other studies have shown promising results with rehabilitation approaches for Long Haul COVID, indicating potential for success in this program.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Long Haul COVID Infection (Documented by PCR or patient report) * Age \>= 18 years old. * At least 12 weeks since the initial COVID Infection. * One or more of the following symptom/signs: Fatigue, Dyspnea, Exercise Intolerance, Post Exertional Malaise and/or Difficulty Breathing. * Able to perform a cardiopulmonary exercise test. Exclusion Criteria: * Patients is not able to perform technically acceptable pulmonary function tests and symptom-limited cardiopulmonary cycle ergometry tests. * Patients who desaturate to SpO2 \<80% on screening incremental exercise testing. * Patients who have completed a pulmonary rehabilitation program in the six weeks prior to the screening visit or patients who are currently in a pulmonary rehabilitation program. * Patients who have taken an investigational drug within one month or six half-lives (whichever is greater) prior to screening visit (Visit 1). * Pregnant or nursing women. * Women of childbearing potential who are not using a highly effective method of birth control. Female patients will be considered of childbearing potential unless surgically sterilized by hysterectomy or bilateral tubal ligation, or post-menopausal for at least two years. * Patients who are currently participating in another interventional study. * Malignancy for which the patient has undergone resection, radiation therapy, or chemotherapy within the last 2 years * Any other significant disease than COVID which, in the opinion of the investigator, may i) put the patient at risk because of participation in the study, ii) influence the results of the study (e.g. Insulin or testosterone therapy, systemic corticosteroids, HIV, etc), iii) cause concern regarding the patient's ability to participate in the study.
Where this trial is running
Torrance, California
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center — Torrance, California, United States (Recruiting)
Study contacts
- Study coordinator: William W Stringer, MD
- Email: wstringer@lundquist.org
- Phone: 424-571-7626
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.