Rehabilitation program for frail older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of a frailty rehabilitation program aimed at improving physical function in community-dwelling older adults aged 65 and above who are frail and at high risk for mobility disability. Participants will be randomly assigned to one of three groups: a control group, an exercise-only group, or a multi-modal rehabilitation group that includes exercise, nutrition, medication review, and supplements. The study will involve 324 participants recruited from YMCA sites, with assessments conducted to evaluate the impact of the rehabilitation program on frailty and sarcopenia. The trial aims to identify essential components of rehabilitation that can help change the trajectory of frailty in older adults.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Community-dwelling ≥65 years of age
* Able to independently ambulate 25m with or without walking aid
* At high risk for mobility disability/functional limitations
* Received medical clearance
* Can arrange transportation to the YMCA up to 2x/week
* Proof of being fully vaccinated against COVID-19 and proof of identification

Exclusion Criteria:

* Unable to speak or understand English
* Currently attending a group exercise program
* Currently in a drug optimization study/program
* Currently taking protein supplements daily
* Significant cognitive impairment where they may have difficulty following two-step commands in group exercise
* Receiving palliative/end of life care
* Unstable angina or heart failure
* Unable to attend for more than 20% of trial duration

Where it's running

• McMaster University - St. Peter's Hospital
  Hamilton, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Alexandra Papaioannou, MD, MSc — McMaster University
• Study coordinator: Sherri Smith
• Email: smithsher@hhsc.ca
• Phone: 905 521 2100

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Home-based multicomponent exercise program for older adults with osteosarcopenia and frailty

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• Frailty-focused prehabilitation before heart surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.