Rehabilitation for upper limb impairment after stroke using action observation and muscle stimulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of a combined rehabilitation approach using Action Observation Therapy (AOT) and Neuromuscular Electrical Stimulation (NMES) for patients with upper limb motor impairment following a stroke. The study aims to determine if this dual intervention is more effective than AOT alone or the observation of non-motor stimuli. Participants will be individuals aged 18 and older who have experienced a unilateral stroke within the last six months and have measurable upper arm motor impairment. The trial will assess improvements in motor function through various rehabilitation protocols.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age over 18 years;
* Upper arm motor impairment after unilateral stroke as verified by MRI or CT;
* Two weeks up to 6 months after stroke;
* Grading of upper arm motor impairment\>2 at Medical Research Council scale (MRC).

Exclusion Criteria:

* Neurological/orthopedic issues that would interfere with upper limb exercises;
* Presence of any medical condition that represents a contraindication to Magnetic Resonance Imaging (MRI) examination or to Transcranial Magnetic Stimulation (TMS);
* Presence of dermatologic issues that will interfere with neuromuscular stimulator;
* Presence of electronic subcutaneous implants;
* Presence of peripheral neuropathy;
* Epilepsy;
* Pregnancy;
* Presence of severe cognitive impairment, including language comprehension detected during the neurological evaluation.

Where it's running

• IRCCS Fondazione Don Carlo Gnocchi
  Milan, Italia, Italy Recruiting

Study contacts

• Study coordinator: Monia Cabinio, Ph.D.
• Email: mcabinio@dongnocchi.it
• Phone: +390240308952

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.