Rehabilitation for people with Guillain-Barré Syndrome

RehabGBs: Rehabilitation in People With Guillain-Barré Syndrome

Not applicable Interventional Centro de Reabilitacao do Norte · NCT05461898

This study tests if a combination of inpatient rehabilitation and breathing exercises can help people with Guillain-Barré Syndrome improve their breathing, strength, and quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment74 (estimated)
Ages18 Years and up
SexAll
SponsorCentro de Reabilitacao do Norte Academic / other
Locations1 site (Vila Nova de Gaia)
Trial IDNCT05461898 on ClinicalTrials.gov

What this trial studies

This study focuses on the rehabilitation of individuals diagnosed with Guillain-Barré Syndrome (GBS), a neurological condition that can lead to significant muscle weakness and respiratory complications. The intervention involves inpatient rehabilitation combined with inspiratory muscle training, aimed at improving respiratory function, exercise capacity, and overall quality of life. The study seeks to establish the effectiveness of this approach in addressing the unique challenges faced by GBS patients, particularly in the context of respiratory muscle weakness. By employing methodologically robust trial designs, the research aims to generate evidence-based insights into rehabilitation practices for this patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with Guillain-Barré Syndrome and are willing to participate in an inpatient rehabilitation program.

Not a fit: Patients with significant cardiac or musculoskeletal diseases, tracheostomized individuals, or those with cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance respiratory function and quality of life for patients with Guillain-Barré Syndrome.

How similar studies have performed: While inspiratory muscle training has shown benefits in other respiratory and neurological conditions, its specific application in Guillain-Barré Syndrome remains largely untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years
* diagnosed with Guillain Barré Syndrome
* willing to participate in an inpatient rehabilitation program
* able to provide informed consent

Exclusion Criteria:

* presence of significant cardiac and musculoskeletal diseases
* tracheostomized patients
* signs of cognitive impairment or current neoplastic or immunological disease which may preclude their participation in the rehabilitation program and participation in any other therapeutic intervention in addition to standard of care.

Where this trial is running

Vila Nova de Gaia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Guillain-Barré SyndromeRehabilitationInspiratory Muscle Training
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.