Rehabilitation for people recovering from tuberculosis lung disease

Rehabilitation of People With Post-tuberculosis Lung Disease

NA · Centro Universitário Augusto Motta · NCT06127641

This study is testing if a 12-week rehabilitation program can help people recovering from tuberculosis lung disease feel better and improve their daily activities compared to standard care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorCentro Universitário Augusto Motta (other)
Locations2 sites (Rio de Janeiro and 1 other locations)
Trial IDNCT06127641 on ClinicalTrials.gov

What this trial studies

This study evaluates the impact of pulmonary rehabilitation on the functionality and health-related quality of life of individuals suffering from post-tuberculosis lung disease (PD-PTB). It involves a randomized controlled trial where participants will be divided into two groups: one receiving standard care and the other undergoing a 12-week pulmonary rehabilitation program. The study will assess functional capacity using the Glittre-ADL test, along with evaluations of lung function, muscle function, fatigue, and overall quality of life. Additionally, an artificial intelligence-based scoring system for PD-PTB severity will be developed based on the collected data.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with clinically stable post-tuberculosis lung disease who can participate in at least 80% of the training sessions.

Not a fit: Patients with significant comorbidities unrelated to PD-PTB or those unable to perform the required tests may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve the quality of life and functional capabilities of patients recovering from tuberculosis lung disease.

How similar studies have performed: Other studies have shown promising results with pulmonary rehabilitation in similar patient populations, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with post-tuberculosis lung disease, clinically stable and able to perform \>80% of training sessions.

Exclusion Criteria:

* Presence of comorbidities not related to PD-PTB.
* Patients with inability to perform TGlittre.
* Patients who have cognitive changes that impair their inclusion in the study.
* Treatment abandonment during the application of the PR protocol.
* Uncontrolled hypertension or use of psychotropic medications.
* Any significant limitations due to osteoarthropathy.
* Having had any orthopedic surgery in the previous year.

Where this trial is running

Rio de Janeiro and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pulmonary Tuberculosis, Pulmonary tuberculosis, Tuberculosis sequelae, Rehabilitation, ADL-Glittre test, Functionality, Quality of life

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.